Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 842 A 407 |
| Chain | Residue |
| A | ASP38 |
| A | ASP234 |
| A | GLY236 |
| A | GLY40 |
| A | PRO76 |
| A | TYR77 |
| A | THR78 |
| A | PHE114 |
| A | ILE132 |
| A | TYR204 |
| A | ILE232 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 842 B 407 |
| Chain | Residue |
| B | LEU36 |
| B | ASP38 |
| B | GLY40 |
| B | PRO76 |
| B | TYR77 |
| B | THR78 |
| B | PHE114 |
| B | TRP121 |
| B | ILE132 |
| B | TYR204 |
| B | ILE232 |
| B | ASP234 |
| B | GLY236 |
| B | THR237 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 842 C 407 |
| Chain | Residue |
| C | LEU36 |
| C | ASP38 |
| C | GLY40 |
| C | PRO76 |
| C | TYR77 |
| C | THR78 |
| C | PHE114 |
| C | TRP121 |
| C | ILE124 |
| C | ILE132 |
| C | TYR204 |
| C | ASP234 |
| C | GLY236 |
| C | THR237 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE35-VAL46 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 21 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"17425515","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19011241","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
