3N3A
Ribonucleotide Reductase Dimanganese(II)-NrdF from Escherichia coli in Complex with Reduced NrdI
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0005515 | molecular_function | protein binding |
| A | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
| A | 0009185 | biological_process | ribonucleoside diphosphate metabolic process |
| A | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
| A | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| B | 0005515 | molecular_function | protein binding |
| B | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
| B | 0009185 | biological_process | ribonucleoside diphosphate metabolic process |
| B | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
| B | 0009265 | biological_process | 2'-deoxyribonucleotide biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0010181 | molecular_function | FMN binding |
| C | 0036211 | biological_process | protein modification process |
| D | 0005515 | molecular_function | protein binding |
| D | 0010181 | molecular_function | FMN binding |
| D | 0036211 | biological_process | protein modification process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 320 |
| Chain | Residue |
| B | GLU98 |
| B | GLU158 |
| B | GLU192 |
| B | HIS195 |
| B | HOH429 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 321 |
| Chain | Residue |
| B | GLU192 |
| B | HOH430 |
| B | ASP67 |
| B | GLU98 |
| B | HIS101 |
| B | GLU158 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN C 134 |
| Chain | Residue |
| B | TYR197 |
| C | SER8 |
| C | SER9 |
| C | SER11 |
| C | GLU12 |
| C | ASN13 |
| C | THR14 |
| C | PRO47 |
| C | SER48 |
| C | TYR49 |
| C | GLY50 |
| C | GLY82 |
| C | ASN83 |
| C | PHE86 |
| C | ALA89 |
| C | TYR90 |
| C | GLY91 |
| C | LEU111 |
| C | HOH135 |
| C | HOH137 |
| C | HOH250 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 320 |
| Chain | Residue |
| A | GLU98 |
| A | GLU158 |
| A | GLU192 |
| A | HIS195 |
| A | MN321 |
| A | HOH388 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 321 |
| Chain | Residue |
| A | ASP67 |
| A | GLU98 |
| A | HIS101 |
| A | GLU158 |
| A | GLU192 |
| A | MN320 |
| A | HOH401 |
| site_id | AC6 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FMN D 134 |
| Chain | Residue |
| A | ARG25 |
| A | TYR197 |
| D | SER8 |
| D | SER9 |
| D | SER11 |
| D | GLU12 |
| D | ASN13 |
| D | THR14 |
| D | PRO47 |
| D | SER48 |
| D | TYR49 |
| D | GLY50 |
| D | GLY82 |
| D | ASN83 |
| D | PHE86 |
| D | ALA89 |
| D | TYR90 |
| D | GLY91 |
| D | LEU111 |
| D | HOH137 |
| D | HOH208 |
| D | HOH264 |
Functional Information from PROSITE/UniProt
| site_id | PS00368 |
| Number of Residues | 17 |
| Details | RIBORED_SMALL Ribonucleotide reductase small subunit signature. MEa.VHArSYssIfstLC |
| Chain | Residue | Details |
| B | MET97-CYS113 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10014","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10014","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| Chain | Residue | Details |
