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3N2Z

The Structure of Human Prolylcarboxypeptidase at 2.80 Angstroms Resolution

Functional Information from GO Data
ChainGOidnamespacecontents
B0002003biological_processangiotensin maturation
B0002155biological_processregulation of thyroid hormone receptor signaling pathway
B0002353biological_processplasma kallikrein-kinin cascade
B0003085biological_processnegative regulation of systemic arterial blood pressure
B0004180molecular_functioncarboxypeptidase activity
B0004181molecular_functionmetallocarboxypeptidase activity
B0004185molecular_functionserine-type carboxypeptidase activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005764cellular_componentlysosome
B0005886cellular_componentplasma membrane
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0008239molecular_functiondipeptidyl-peptidase activity
B0016787molecular_functionhydrolase activity
B0035577cellular_componentazurophil granule membrane
B0042593biological_processglucose homeostasis
B0043535biological_processregulation of blood vessel endothelial cell migration
B0045178cellular_componentbasal part of cell
B0060055biological_processangiogenesis involved in wound healing
B0070008molecular_functionserine-type exopeptidase activity
B0070062cellular_componentextracellular exosome
B0097009biological_processenergy homeostasis
B0101003cellular_componentficolin-1-rich granule membrane
B2000377biological_processregulation of reactive oxygen species metabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: Charge relay system => ECO:0000269|PubMed:20540760
ChainResidueDetails
BSER179
BASP430
BHIS455

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN47

site_idSWS_FT_FI3
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:20540760
ChainResidueDetails
BASN101
BASN336
BASN345

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:20540760
ChainResidueDetails
BASN317
BASN415

237735

PDB entries from 2025-06-18

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