3N2Z
The Structure of Human Prolylcarboxypeptidase at 2.80 Angstroms Resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002003 | biological_process | angiotensin maturation |
| B | 0003085 | biological_process | negative regulation of systemic arterial blood pressure |
| B | 0004180 | molecular_function | carboxypeptidase activity |
| B | 0004181 | molecular_function | metallocarboxypeptidase activity |
| B | 0004185 | molecular_function | serine-type carboxypeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005764 | cellular_component | lysosome |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0035577 | cellular_component | azurophil granule membrane |
| B | 0043535 | biological_process | regulation of blood vessel endothelial cell migration |
| B | 0045178 | cellular_component | basal part of cell |
| B | 0060055 | biological_process | angiogenesis involved in wound healing |
| B | 0070008 | molecular_function | serine-type exopeptidase activity |
| B | 0070062 | cellular_component | extracellular exosome |
| B | 0101003 | cellular_component | ficolin-1-rich granule membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 140 |
| Details | Region: {"description":"SKS domain"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"20540760","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"20540760","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20540760","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
