3N2W

Crystal structure of the N-terminal beta-aminopeptidase BapA from Sphingosinicella xenopeptidilytica

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0006508	biological_process	proteolysis
A	0042597	cellular_component	periplasmic space
A	0042802	molecular_function	identical protein binding
B	0004177	molecular_function	aminopeptidase activity
B	0006508	biological_process	proteolysis
B	0042597	cellular_component	periplasmic space
B	0042802	molecular_function	identical protein binding
C	0004177	molecular_function	aminopeptidase activity
C	0006508	biological_process	proteolysis
C	0042597	cellular_component	periplasmic space
C	0042802	molecular_function	identical protein binding
D	0004177	molecular_function	aminopeptidase activity
D	0006508	biological_process	proteolysis
D	0042597	cellular_component	periplasmic space
D	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL A 374

Chain	Residue
A	VAL88
D	ASN314
D	ASP315
A	GLY89
A	GLN90
A	PRO263
A	HIS299
A	ILE301
A	PRO307
D	MET262
D	HIS264

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 375

Chain	Residue
A	PHE124
A	SER125
A	ARG126
A	LEU127

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 376

Chain	Residue
A	GLY285
A	ALA286
A	LEU287
A	SER288
A	HOH501
A	HOH1067
C	SER318
C	ASN322

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 377

Chain	Residue
A	GLU224
A	ILE365
A	ALA368
A	ARG369
A	HOH1345
A	HOH1403

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL B 374

Chain	Residue
B	VAL88
B	GLY89
B	GLN90
B	PRO263
B	HIS299
B	ILE301
B	PRO307
C	MET262
C	HIS264
C	ASN314
C	ASP315

---

site_id	AC6
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL C 374

Chain	Residue
B	MET262
B	HIS264
B	ASN314
B	ASP315
C	VAL88
C	GLY89
C	GLN90
C	PRO263
C	HIS299
C	ILE301
C	PRO307

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL C 375

Chain	Residue
C	THR76
C	GLY77
C	GLU133
C	THR134
C	LEU135
C	SER250
C	LEU287
C	SO4379
C	HOH453
D	LEU128

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 376

Chain	Residue
C	LEU84
C	PHE124
C	SER125
C	LEU127

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 C 377

Chain	Residue
A	SER318
A	ASN322
C	GLY285
C	ALA286
C	LEU287
C	SER288
C	HOH421
C	HOH1093

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 378

Chain	Residue
B	LYS306
C	ILE312
C	ILE313
C	ASN314
C	ASP317
C	HOH771

---

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 C 379

Chain	Residue
C	LEU135
C	ASN207
C	SER250
C	LEU287
C	SER288
C	GOL375
C	HOH719
C	HOH1093

---

site_id	BC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL D 374

Chain	Residue
A	MET262
A	HIS264
A	ASN314
A	ASP315
D	VAL88
D	GLY89
D	GLN90
D	PRO263
D	HIS299
D	ILE301
D	PRO307

---

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 375

Chain	Residue
D	SER125
D	ARG126
D	LEU127
D	PHE124

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 376

Chain	Residue
B	SER318
B	ASN322
D	GLY285
D	ALA286
D	LEU287
D	SER288
D	HOH489

---

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 377

Chain	Residue
D	GLY13
D	THR14
D	HOH407
D	HOH454
D	HOH513

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile => ECO:0000303|PubMed:22980995

Chain	Residue	Details
A	SER250
B	SER250
C	SER250
D	SER250

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Proton donor/acceptor => ECO:0000303|PubMed:22980995

Chain	Residue	Details
A	SER288
A	GLU290
B	SER288
B	GLU290
C	SER288
C	GLU290
D	SER288
D	GLU290

---