Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004326 | molecular_function | tetrahydrofolylpolyglutamate synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016881 | molecular_function | acid-amino acid ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ADP A 1001 |
| Chain | Residue |
| A | THR57 |
| A | ASP314 |
| A | VAL315 |
| A | ALA316 |
| A | HIS320 |
| A | ALA321 |
| A | TYR324 |
| A | HOH488 |
| A | MG501 |
| A | HOH507 |
| A | HOH602 |
| A | ASN58 |
| A | GLY59 |
| A | LYS60 |
| A | GLY61 |
| A | THR62 |
| A | GLU146 |
| A | ASN269 |
| A | ARG301 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 501 |
| Chain | Residue |
| A | SER83 |
| A | GLU146 |
| A | HOH602 |
| A | HOH619 |
| A | HOH633 |
| A | ADP1001 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 701 |
| Chain | Residue |
| A | SER83 |
| A | HOH640 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 702 |
| Chain | Residue |
| A | THR57 |
| A | ALA170 |
| A | TYR179 |
| A | ILE184 |
| A | LYS188 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | GLU68 |
| A | ARG94 |
| A | GLY97 |
| A | SER297 |
| A | HOH467 |
| A | HOH638 |
Functional Information from PROSITE/UniProt
| site_id | PS01012 |
| Number of Residues | 16 |
| Details | FOLYLPOLYGLU_SYNT_2 Folylpolyglutamate synthase signature 2. ILEvGLGGrlDaTnIV |
| Chain | Residue | Details |
| A | ILE144-VAL159 | |
