3N0U

Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
A	0006281	biological_process	DNA repair
A	0006284	biological_process	base-excision repair
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
A	0016829	molecular_function	lyase activity
A	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
B	0003824	molecular_function	catalytic activity
B	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
B	0006281	biological_process	DNA repair
B	0006284	biological_process	base-excision repair
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
B	0016829	molecular_function	lyase activity
B	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C	0003824	molecular_function	catalytic activity
C	0003906	molecular_function	DNA-(apurinic or apyrimidinic site) endonuclease activity
C	0006281	biological_process	DNA repair
C	0006284	biological_process	base-excision repair
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0016799	molecular_function	hydrolase activity, hydrolyzing N-glycosyl compounds
C	0016829	molecular_function	lyase activity
C	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 208

Chain	Residue
A	LEU119
A	VAL120
A	ALA123
A	ILE126
A	HOH277
A	HOH399

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA B 208

Chain	Residue
B	ILE126
B	HOH267
B	HOH298
B	LEU119
B	VAL120
B	ALA123

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA C 208

Chain	Residue
C	LEU119
C	VAL120
C	ALA123
C	ILE126
C	HOH334
C	HOH415

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00241

Chain	Residue	Details
A	LYS129
A	ASP147
B	LYS129
B	ASP147
C	LYS129
C	ASP147

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site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Important for guanine/8-oxoguanine distinction => ECO:0000255|HAMAP-Rule:MF_00241

Chain	Residue	Details
A	LYS207
B	LYS207
C	LYS207

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