3MVS

Structure of the N-terminus of Cadherin 23

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005886	cellular_component	plasma membrane
A	0007155	biological_process	cell adhesion
A	0007156	biological_process	homophilic cell-cell adhesion
A	0016020	cellular_component	membrane
A	0098609	biological_process	cell-cell adhesion

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 211

Chain	Residue
A	GLU21
A	ASP71
A	GLU73
A	ASP104
A	HOH335
A	HOH395

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 212

Chain	Residue
A	VAL102
A	ASP104
A	ASP137
A	GLU21
A	GLU73
A	ASP101

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 213

Chain	Residue
A	ASN103
A	ASN105
A	ASP135
A	ASP137
A	GLY141
A	ASP186

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 214

Chain	Residue
A	GLU120
A	GLU173
A	ASP205
A	MET206
A	ASP208
A	HOH486

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 215

Chain	Residue
A	GLU120
A	ASP171
A	GLU173
A	ASP208
A	HOH338
A	HOH485

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 216

Chain	Residue
A	ASN3
A	ARG4
A	ASP36
A	ASP38
A	ASP40
A	ASP86

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 217

Chain	Residue
A	ASN3
A	ASP38
A	ASP40
A	GLN88

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 218

Chain	Residue
A	ASN39

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 219

Chain	Residue
A	LYS75
A	SER76
A	GLU77
A	ASN198
A	HOH277
A	HOH366

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 220

Chain	Residue
A	PRO127

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 221

Chain	Residue
A	THR9
A	ASN10
A	ASP14

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 222

Chain	Residue
A	GLU21
A	ASP22
A	THR23
A	PRO69
A	HOH375

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 223

Chain	Residue
A	GLU58
A	HOH274
A	HOH510

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 224

Chain	Residue
A	ASN111
A	ILE130
A	HOH380

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 225

Chain	Residue
A	VAL131
A	ASN132
A	TYR146
A	ARG161
A	GLU173
A	HOH441

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 226

Chain	Residue
A	PHE12
A	THR30

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 227

Chain	Residue
A	ASN3
A	HOH279

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 228

Chain	Residue
A	PHE8
A	ILE91
A	ARG93
A	HOH438

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 229

Chain	Residue
A	VAL57
A	GLN168
A	HOH275
A	HOH334

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 230

Chain	Residue
A	ALA106
A	PRO107
A	THR108
A	HOH342

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 231

Chain	Residue
A	ASN111
A	HOH431

---

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 232

Chain	Residue
A	LEU138
A	GLY139
A	EDO235
A	HOH378

---

site_id	CC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 233

Chain	Residue
A	VAL46
A	SER47
A	GLY48
A	GLU49
A	PRO123
A	VAL124
A	GLU169
A	HOH497

---

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 234

Chain	Residue
A	MET37
A	HOH483
A	ARG4

---

site_id	CC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO A 235

Chain	Residue
A	ASP135
A	PRO136
A	ASP137
A	GLY142
A	VAL174
A	THR175
A	EDO232
A	EDO238
A	HOH299
A	HOH319

---

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 236

Chain	Residue
A	ASP205
A	MET206
A	GLN207
A	EDO237

---

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 237

Chain	Residue
A	ASP205
A	EDO236

---

site_id	DC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 238

Chain	Residue
A	THR134
A	ASP135
A	PRO136
A	VAL174
A	GLN176
A	EDO235
A	HOH387
A	HOH400

---

Functional Information from PROSITE/UniProt

site_id	PS00232
Number of Residues	11
Details	CADHERIN_1 Cadherin domain signature. IqVgDvNDNaP

Chain	Residue	Details
A	ILE97-PRO107

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	Domain: {"description":"Cadherin 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00043","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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