Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004013 | molecular_function | adenosylhomocysteinase activity |
| B | 0004013 | molecular_function | adenosylhomocysteinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE NAD A 1 |
| Chain | Residue |
| A | VAL256 |
| A | ASP343 |
| A | CYS346 |
| A | CYS373 |
| A | THR374 |
| A | GLY375 |
| A | ASN376 |
| A | VAL379 |
| A | MET397 |
| A | GLY398 |
| A | HIS399 |
| A | CYS292 |
| A | ASN444 |
| B | GLN511 |
| B | LYS524 |
| B | TYR528 |
| A | GLY318 |
| A | GLY320 |
| A | GLU321 |
| A | VAL322 |
| A | THR340 |
| A | GLU341 |
| A | ILE342 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE NAD B 1 |
| Chain | Residue |
| A | GLN511 |
| A | LYS524 |
| A | TYR528 |
| B | CYS292 |
| B | GLY318 |
| B | GLY320 |
| B | GLU321 |
| B | VAL322 |
| B | THR340 |
| B | GLU341 |
| B | ILE342 |
| B | ASP343 |
| B | CYS346 |
| B | CYS373 |
| B | THR374 |
| B | GLY375 |
| B | ASN376 |
| B | VAL379 |
| B | MET397 |
| B | GLY398 |
| B | HIS399 |
Functional Information from PROSITE/UniProt
| site_id | PS00738 |
| Number of Residues | 15 |
| Details | ADOHCYASE_1 S-adenosyl-L-homocysteine hydrolase signature 1. ACNiYSTQNeVAAAL |
| Chain | Residue | Details |
| A | ALA176-LEU190 | |
| site_id | PS00739 |
| Number of Residues | 18 |
| Details | ADOHCYASE_2 S-adenosyl-L-homocysteine hydrolase signature 2. GKqvvVcGYGeVGKGccA |
| Chain | Residue | Details |
| A | GLY311-ALA328 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 126 |
| Details | Region: {"description":"Interaction with BCL2L10","evidences":[{"source":"PubMed","id":"27995898","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 167 |
| Details | Region: {"description":"NAD binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | Region: {"description":"PDZ-binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25237103","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18669648","evidenceCode":"ECO:0007744"}]} |
