Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE STI A 1 |
| Chain | Residue |
| A | HOH75 |
| A | MET318 |
| A | ILE360 |
| A | HIS361 |
| A | LEU370 |
| A | ALA380 |
| A | ASP381 |
| A | PHE382 |
| A | VAL256 |
| A | ALA269 |
| A | LYS271 |
| A | GLU286 |
| A | MET290 |
| A | ILE293 |
| A | VAL299 |
| A | THR315 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MS9 A 516 |
| Chain | Residue |
| A | HOH44 |
| A | ALA337 |
| A | LEU341 |
| A | LEU429 |
| A | ALA433 |
| A | GLY463 |
| A | PRO465 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 2 |
| Chain | Residue |
| A | HOH131 |
| A | ILE360 |
| A | HOH535 |
| A | HOH594 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 4 |
| Chain | Residue |
| A | THR319 |
| A | GLY372 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 5 |
| Chain | Residue |
| A | TYR253 |
| A | GLY321 |
| A | ASN322 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE STI B 1 |
| Chain | Residue |
| B | HOH165 |
| B | ALA269 |
| B | LYS271 |
| B | GLU286 |
| B | MET290 |
| B | VAL299 |
| B | ILE313 |
| B | THR315 |
| B | PHE317 |
| B | MET318 |
| B | ILE360 |
| B | HIS361 |
| B | ARG362 |
| B | ALA380 |
| B | ASP381 |
| B | PHE382 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MS9 B 516 |
| Chain | Residue |
| B | ALA337 |
| B | LEU341 |
| B | LEU429 |
| B | ILE432 |
| B | ALA433 |
| B | GLY463 |
| B | PRO465 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 3 |
| Chain | Residue |
| B | HOH151 |
| B | HOH214 |
| B | PHE359 |
| B | ILE360 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 6 |
| Chain | Residue |
| B | TYR253 |
| B | GLY321 |
| B | ASN322 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGGGQYGEVYeGvwkkyslt..........VAVK |
| Chain | Residue | Details |
| A | LEU248-LYS271 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FIHrDLAARNCLV |
| Chain | Residue | Details |
| A | PHE359-VAL371 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP363 | |
| B | ASP363 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| B | LEU248 | |
| B | GLU316 | |
| A | LEU248 | |
| A | GLU316 | |
| Chain | Residue | Details |
| A | LYS271 | |
| B | LYS271 | |
| Chain | Residue | Details |
| A | SER229 | |
| B | SER229 | |
| Chain | Residue | Details |
| A | TYR253 | |
| A | TYR257 | |
| A | TYR413 | |
| B | TYR253 | |
| B | TYR257 | |
| B | TYR413 | |
| Chain | Residue | Details |
| A | TYR393 | |
| B | TYR393 | |
| Chain | Residue | Details |
| A | SER446 | |
| B | SER446 | |
