3MPJ
Structure of the glutaryl-coenzyme A dehydrogenase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| D | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| E | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| F | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0003995 | molecular_function | acyl-CoA dehydrogenase activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016627 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors |
| G | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE FAD A 400 |
| Chain | Residue |
| A | MET92 |
| A | LYS204 |
| A | MET365 |
| A | VAL366 |
| A | GLU367 |
| A | SER369 |
| A | ASN371 |
| A | ILE372 |
| A | MET375 |
| A | HOH7003 |
| A | HOH7004 |
| A | PHE126 |
| A | HOH7050 |
| A | HOH7182 |
| A | HOH7236 |
| A | HOH7286 |
| A | HOH7290 |
| B | ARG271 |
| B | GLN273 |
| B | PHE274 |
| B | ILE278 |
| B | PHE281 |
| A | ILE128 |
| B | GLN282 |
| B | ASN284 |
| B | ARG340 |
| B | ILE341 |
| B | GLY343 |
| B | ALA344 |
| B | HOH7079 |
| A | THR129 |
| A | GLY134 |
| A | SER135 |
| A | TRP159 |
| A | ILE160 |
| A | SER161 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | ASN35 |
| A | LYS204 |
| A | HIS208 |
| A | HOH8012 |
| site_id | AC3 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE FAD B 400 |
| Chain | Residue |
| A | ARG271 |
| A | GLN273 |
| A | PHE274 |
| A | ILE278 |
| A | PHE281 |
| A | GLN282 |
| A | ASN284 |
| A | ARG340 |
| A | ILE341 |
| A | GLY343 |
| A | ALA344 |
| A | TYR345 |
| B | MET92 |
| B | PHE126 |
| B | ILE128 |
| B | THR129 |
| B | GLY134 |
| B | SER135 |
| B | TRP159 |
| B | ILE160 |
| B | SER161 |
| B | LYS204 |
| B | MET365 |
| B | VAL366 |
| B | GLU367 |
| B | SER369 |
| B | ASN371 |
| B | MET375 |
| B | HOH7006 |
| B | HOH7011 |
| B | HOH7012 |
| B | HOH7021 |
| B | HOH7080 |
| B | HOH7129 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| B | ASN35 |
| B | LYS204 |
| B | HIS208 |
| B | HOH7361 |
| site_id | AC5 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD D 400 |
| Chain | Residue |
| E | ARG271 |
| E | GLN273 |
| E | PHE274 |
| E | PHE281 |
| E | ASN284 |
| E | ARG340 |
| E | ILE341 |
| E | GLY343 |
| E | ALA344 |
| E | TYR345 |
| G | GLN282 |
| D | PHE126 |
| D | ILE128 |
| D | THR129 |
| D | GLY134 |
| D | SER135 |
| D | TRP159 |
| D | ILE160 |
| D | SER161 |
| D | MET365 |
| D | VAL366 |
| D | GLU367 |
| D | SER369 |
| D | ASN371 |
| D | MET375 |
| D | HOH7422 |
| D | HOH7424 |
| D | HOH7436 |
| D | HOH7481 |
| D | HOH7586 |
| D | HOH7689 |
| D | HOH7981 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 401 |
| Chain | Residue |
| D | LYS204 |
| D | HIS208 |
| site_id | AC7 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FAD E 400 |
| Chain | Residue |
| D | ARG271 |
| D | GLN273 |
| D | PHE274 |
| D | PHE281 |
| D | ASN284 |
| D | ARG340 |
| D | ILE341 |
| D | GLY343 |
| D | ALA344 |
| E | MET92 |
| E | PHE126 |
| E | ILE128 |
| E | THR129 |
| E | GLY134 |
| E | SER135 |
| E | TRP159 |
| E | SER161 |
| E | MET365 |
| E | VAL366 |
| E | GLU367 |
| E | SER369 |
| E | ASN371 |
| E | MET375 |
| E | HOH7692 |
| E | HOH7693 |
| E | HOH7849 |
| E | HOH7973 |
| F | GLN282 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL E 401 |
| Chain | Residue |
| E | ASN35 |
| E | LYS204 |
| E | HIS208 |
| site_id | AC9 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD F 400 |
| Chain | Residue |
| E | GLN282 |
| F | MET92 |
| F | PHE126 |
| F | ILE128 |
| F | THR129 |
| F | GLY134 |
| F | SER135 |
| F | TRP159 |
| F | SER161 |
| F | MET365 |
| F | VAL366 |
| F | GLU367 |
| F | SER369 |
| F | ASN371 |
| F | MET375 |
| F | HOH7403 |
| F | HOH7404 |
| F | HOH7421 |
| F | HOH7551 |
| F | HOH7705 |
| G | ARG271 |
| G | GLN273 |
| G | PHE274 |
| G | PHE281 |
| G | ASN284 |
| G | ARG340 |
| G | ILE341 |
| G | GLY343 |
| G | ALA344 |
| G | HOH7405 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL F 401 |
| Chain | Residue |
| F | ASN35 |
| F | LYS204 |
| F | HIS208 |
| F | HOH7527 |
| site_id | BC2 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD G 400 |
| Chain | Residue |
| D | GLN282 |
| F | ARG271 |
| F | GLN273 |
| F | PHE274 |
| F | PHE281 |
| F | ASN284 |
| F | ARG340 |
| F | ILE341 |
| F | GLY343 |
| F | ALA344 |
| F | HOH7433 |
| G | MET92 |
| G | PHE126 |
| G | ILE128 |
| G | THR129 |
| G | GLY134 |
| G | SER135 |
| G | TRP159 |
| G | SER161 |
| G | MET365 |
| G | VAL366 |
| G | GLU367 |
| G | SER369 |
| G | ASN371 |
| G | MET375 |
| G | HOH7406 |
| G | HOH7445 |
| G | HOH7533 |
| G | HOH7593 |
| G | HOH7604 |
| G | HOH7653 |
| G | HOH7976 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL G 401 |
| Chain | Residue |
| G | LYS204 |
| G | HIS208 |
Functional Information from PROSITE/UniProt
| site_id | PS00072 |
| Number of Residues | 13 |
| Details | ACYL_COA_DH_1 Acyl-CoA dehydrogenases signature 1. GITEpdAGSDvmA |
| Chain | Residue | Details |
| A | GLY127-ALA139 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 120 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20486657","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
