3MOG

Crystal structure of 3-hydroxybutyryl-CoA dehydrogenase from Escherichia coli K12 substr. MG1655

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003857	molecular_function	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
A	0010124	biological_process	phenylacetate catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0032787	biological_process	monocarboxylic acid metabolic process
A	0070403	molecular_function	NAD+ binding
B	0003857	molecular_function	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
B	0010124	biological_process	phenylacetate catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0032787	biological_process	monocarboxylic acid metabolic process
B	0070403	molecular_function	NAD+ binding
C	0003857	molecular_function	(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0008691	molecular_function	3-hydroxybutyryl-CoA dehydrogenase activity
C	0010124	biological_process	phenylacetate catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0032787	biological_process	monocarboxylic acid metabolic process
C	0070403	molecular_function	NAD+ binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 484

Chain	Residue
A	ARG196
A	ASN242

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 484

Chain	Residue
B	ARG196
B	ASN242

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL B 485

Chain	Residue
B	GLU232
B	TYR283
B	TRP285
B	ARG289

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 484

Chain	Residue
C	ASN242
C	ARG196

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site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL C 485

Chain	Residue
C	GLU232
C	ASP284
C	TRP285
C	ARG289

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Functional Information from PROSITE/UniProt

site_id	PS00067
Number of Residues	26
Details	3HCDH 3-hydroxyacyl-CoA dehydrogenase signature. StpGFIvNRvarPYYseawraLEeqV

Chain	Residue	Details
A	SER185-VAL210

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