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3MNB

Investigation of global and local effects of radiation damage on porcine pancreatic elastase. First stage of radiation damage

Functional Information from GO Data
ChainGOidnamespacecontents
A0004252molecular_functionserine-type endopeptidase activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006508biological_processproteolysis
A0008236molecular_functionserine-type peptidase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE NA A 280
ChainResidue
AGLU70
AASN72
AGLN75
AASN77
AGLU80
AHOH518
AHOH560

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 290
ChainResidue
AARG230
ASER232
AALA233
AHOH456
AHOH585
AHOH610
AHOH645
AGLY127
AARG145

site_idAC3
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 A 295
ChainResidue
AHIS57
AGLN192
AGLY193
ASER195
AHOH298
AHOH303
AHOH614
AHOH700
AHOH710
AHOH745

Functional Information from PROSITE/UniProt
site_idPS00134
Number of Residues6
DetailsTRYPSIN_HIS Serine proteases, trypsin family, histidine active site. MTAAHC
ChainResidueDetails
AMET53-CYS58

site_idPS00135
Number of Residues12
DetailsTRYPSIN_SER Serine proteases, trypsin family, serine active site. SGcqGDSGGPLH
ChainResidueDetails
ASER189-HIS200

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Charge relay system => ECO:0000269|PubMed:4578945, ECO:0000269|PubMed:5415110
ChainResidueDetails
AHIS57

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: Charge relay system => ECO:0000269|PubMed:5415110
ChainResidueDetails
AASP102
ASER195

site_idSWS_FT_FI3
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:7656008, ECO:0007744|PDB:1ELA, ECO:0007744|PDB:1ELB, ECO:0007744|PDB:1ELC
ChainResidueDetails
AGLU70
AASN72
AGLN75
AGLU80

226707

PDB entries from 2024-10-30

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