3MMU
Crystal structure of endoglucanase Cel5A from the hyperthermophilic Thermotoga maritima
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000272 | biological_process | polysaccharide catabolic process |
| A | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0009251 | biological_process | glucan catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0000272 | biological_process | polysaccharide catabolic process |
| B | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0009251 | biological_process | glucan catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0000272 | biological_process | polysaccharide catabolic process |
| C | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| C | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0009251 | biological_process | glucan catabolic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| D | 0000272 | biological_process | polysaccharide catabolic process |
| D | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| D | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0009251 | biological_process | glucan catabolic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| E | 0000272 | biological_process | polysaccharide catabolic process |
| E | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| E | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0009251 | biological_process | glucan catabolic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| F | 0000272 | biological_process | polysaccharide catabolic process |
| F | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| F | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0009251 | biological_process | glucan catabolic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| G | 0000272 | biological_process | polysaccharide catabolic process |
| G | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| G | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0009251 | biological_process | glucan catabolic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| H | 0000272 | biological_process | polysaccharide catabolic process |
| H | 0004338 | molecular_function | glucan exo-1,3-beta-glucosidase activity |
| H | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0009251 | biological_process | glucan catabolic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 318 |
| Chain | Residue |
| A | HIS96 |
| A | GLU98 |
| A | HOH582 |
| B | HOH769 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 319 |
| Chain | Residue |
| A | GLU99 |
| A | HOH1368 |
| B | GLU99 |
| B | HOH1367 |
| B | HOH1369 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 320 |
| Chain | Residue |
| A | GLU136 |
| A | GLU253 |
| A | HOH596 |
| A | HOH606 |
| A | HOH776 |
| A | HOH1027 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI A 321 |
| Chain | Residue |
| A | GLU144 |
| A | HOH672 |
| H | GLU78 |
| H | HOH1012 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI A 322 |
| Chain | Residue |
| A | ASP226 |
| A | HIS230 |
| A | HOH774 |
| G | ASP227 |
| G | HOH668 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI A 323 |
| Chain | Residue |
| A | GLU202 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI A 324 |
| Chain | Residue |
| A | ASP305 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI A 325 |
| Chain | Residue |
| A | HIS205 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI A 326 |
| Chain | Residue |
| B | HOH1237 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 318 |
| Chain | Residue |
| A | HOH601 |
| B | HIS96 |
| B | GLU98 |
| B | HOH584 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 319 |
| Chain | Residue |
| B | GLU136 |
| B | GLU253 |
| B | HOH611 |
| B | HOH775 |
| B | HOH1249 |
| B | HOH1250 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI B 320 |
| Chain | Residue |
| B | GLU78 |
| B | HOH638 |
| G | GLU144 |
| G | HOH631 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 321 |
| Chain | Residue |
| B | GLU180 |
| B | HOH1263 |
| H | GLU180 |
| H | LYS244 |
| H | HOH378 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NI B 322 |
| Chain | Residue |
| B | GLU202 |
| B | ARG220 |
| B | HOH595 |
| B | HOH1288 |
| H | ASP226 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI B 323 |
| Chain | Residue |
| B | HIS205 |
| B | HOH1249 |
| site_id | BC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI B 324 |
| Chain | Residue |
| B | GLU127 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD C 318 |
| Chain | Residue |
| C | HIS96 |
| C | GLU98 |
| C | HOH578 |
| C | HOH586 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD C 319 |
| Chain | Residue |
| C | GLU99 |
| C | HOH1370 |
| C | HOH1371 |
| D | GLU99 |
| D | HOH1372 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD C 320 |
| Chain | Residue |
| C | GLU136 |
| C | GLU253 |
| C | HOH501 |
| C | HOH598 |
| C | HOH623 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI C 321 |
| Chain | Residue |
| C | GLU144 |
| C | HOH962 |
| F | GLU78 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI C 322 |
| Chain | Residue |
| C | ASP226 |
| C | HIS230 |
| E | ASP227 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI C 323 |
| Chain | Residue |
| C | HIS205 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI C 324 |
| Chain | Residue |
| C | MET69 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI C 325 |
| Chain | Residue |
| C | ASN140 |
| D | HOH1294 |
| site_id | CC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI C 326 |
| Chain | Residue |
| C | GLU127 |
| site_id | CC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD D 318 |
| Chain | Residue |
| D | HIS96 |
| D | GLU98 |
| D | HOH592 |
| D | HOH1241 |
| site_id | CC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD D 319 |
| Chain | Residue |
| D | GLU136 |
| D | GLU253 |
| D | HOH814 |
| D | HOH1011 |
| D | HOH1252 |
| D | HOH1319 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI D 320 |
| Chain | Residue |
| D | GLU78 |
| D | HOH436 |
| D | HOH659 |
| E | GLU144 |
| site_id | DC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI D 321 |
| Chain | Residue |
| D | GLU127 |
| D | HOH1266 |
| D | HOH1267 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI D 322 |
| Chain | Residue |
| D | HIS205 |
| site_id | DC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD E 318 |
| Chain | Residue |
| E | GLU98 |
| E | HOH499 |
| E | HOH621 |
| E | HOH771 |
| E | HIS96 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD E 319 |
| Chain | Residue |
| E | GLU99 |
| E | HOH1374 |
| F | GLU99 |
| F | HOH585 |
| site_id | DC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD E 320 |
| Chain | Residue |
| E | GLU136 |
| E | GLU253 |
| E | HOH616 |
| E | HOH666 |
| E | HOH788 |
| site_id | DC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI E 321 |
| Chain | Residue |
| C | HOH1330 |
| E | GLU78 |
| E | HOH1331 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI E 322 |
| Chain | Residue |
| E | HIS205 |
| E | HOH788 |
| site_id | DC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI E 323 |
| Chain | Residue |
| E | MET69 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI E 324 |
| Chain | Residue |
| E | GLU127 |
| E | HOH662 |
| site_id | EC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD F 318 |
| Chain | Residue |
| E | HOH614 |
| F | HIS96 |
| F | GLU98 |
| F | HOH579 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD F 319 |
| Chain | Residue |
| F | GLU136 |
| F | GLU253 |
| F | HOH610 |
| F | HOH649 |
| F | HOH663 |
| F | HOH1062 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI F 320 |
| Chain | Residue |
| F | ASP226 |
| F | HIS230 |
| site_id | EC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI F 321 |
| Chain | Residue |
| F | TYR198 |
| F | HIS205 |
| site_id | EC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI F 322 |
| Chain | Residue |
| F | HOH335 |
| site_id | EC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI F 323 |
| Chain | Residue |
| F | GLU127 |
| site_id | EC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD G 318 |
| Chain | Residue |
| G | HIS96 |
| G | GLU98 |
| G | HOH580 |
| G | HOH597 |
| site_id | EC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD G 319 |
| Chain | Residue |
| G | GLU99 |
| G | HOH1361 |
| G | HOH1362 |
| H | GLU99 |
| H | HOH1363 |
| site_id | FC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD G 320 |
| Chain | Residue |
| G | GLU136 |
| G | GLU253 |
| G | HOH589 |
| G | HOH605 |
| G | HOH688 |
| G | HOH1351 |
| site_id | FC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NI G 321 |
| Chain | Residue |
| G | GLU202 |
| site_id | FC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI G 322 |
| Chain | Residue |
| A | ASP227 |
| G | ASP226 |
| G | HIS230 |
| G | HOH830 |
| site_id | FC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI G 323 |
| Chain | Residue |
| G | HIS205 |
| G | HOH1351 |
| site_id | FC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI G 324 |
| Chain | Residue |
| G | GLU127 |
| G | HOH593 |
| site_id | FC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD H 318 |
| Chain | Residue |
| H | HIS96 |
| H | GLU98 |
| H | HOH599 |
| H | HOH602 |
| site_id | FC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD H 319 |
| Chain | Residue |
| H | GLU136 |
| H | GLU253 |
| H | HOH583 |
| H | HOH824 |
| H | HOH826 |
| H | HOH1322 |
| site_id | FC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NI H 320 |
| Chain | Residue |
| B | ASP226 |
| H | GLU202 |
| H | HOH624 |
| H | HOH657 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI H 321 |
| Chain | Residue |
| H | GLU127 |
| H | HOH1264 |
| H | HOH1265 |
| site_id | GC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NI H 322 |
| Chain | Residue |
| H | HIS205 |
| H | HOH1230 |
| site_id | GC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI H 323 |
| Chain | Residue |
| H | MET69 |
| H | HOH608 |
| H | HOH1190 |
Functional Information from PROSITE/UniProt
| site_id | PS00659 |
| Number of Residues | 10 |
| Details | GLYCOSYL_HYDROL_F5 Glycosyl hydrolases family 5 signature. LFFEILNEPH |
| Chain | Residue | Details |
| A | LEU129-HIS138 |
