3MLP

Early B-cell Factor 1 (Ebf1) bound to DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
E	0003677	molecular_function	DNA binding
E	0003700	molecular_function	DNA-binding transcription factor activity
E	0006355	biological_process	regulation of DNA-templated transcription
F	0003677	molecular_function	DNA binding
F	0003700	molecular_function	DNA-binding transcription factor activity
F	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 501

Chain	Residue
A	HIS157
A	CYS161
A	CYS164
A	CYS170

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CIT A 1

Chain	Residue
A	HOH448
A	HOH453
E	LYS258
E	ASP278
E	HIS301
A	HIS53
A	PHE54
A	ALA227
A	VAL228
A	HOH431

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CIT A 3

Chain	Residue
A	VAL90
A	GLY91
A	LYS97
A	HIS109
A	ARG111

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 501

Chain	Residue
B	HIS157
B	CYS161
B	CYS164
B	CYS170

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CIT B 4

Chain	Residue
A	GLU264
A	GLY265
A	TRP266
A	THR338
B	PHE349
B	GLU369
B	HOH442

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 501

Chain	Residue
E	HIS157
E	CYS161
E	CYS164
E	CYS170

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE CIT E 2

Chain	Residue
A	LYS258
A	ASP278
E	HOH21
E	ALA52
E	HIS53
E	PHE54
E	ALA227
E	VAL228

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 501

Chain	Residue
F	HIS157
F	CYS161
F	CYS164
F	CYS170

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CIT F 6

Chain	Residue
F	VAL36
F	LEU37
F	ASP38
F	ARG121
F	THR122
F	GLU123

---

Functional Information from PROSITE/UniProt

site_id	PS01345
Number of Residues	10
Details	COE COE family signature. CSRCCDKKSC

Chain	Residue	Details
A	CYS161-CYS170

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	332
Details	Domain: {"description":"IPT/TIG"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	76
Details	Zinc finger: {"description":"C5-type","evidences":[{"source":"PubMed","id":"20876732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	52
Details	Region: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"20876732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"Interaction with DNA","evidences":[{"source":"PubMed","id":"20876732","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MLN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MLP","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---