3MHG
Dihydroxyacetone phosphate carbanion intermediate in tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005988 | biological_process | lactose metabolic process |
| A | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| A | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| A | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| A | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| A | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| B | 0005988 | biological_process | lactose metabolic process |
| B | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| B | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| B | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| B | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| B | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| C | 0005988 | biological_process | lactose metabolic process |
| C | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| C | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| C | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| C | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| C | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
| D | 0005988 | biological_process | lactose metabolic process |
| D | 0009024 | molecular_function | tagatose-6-phosphate kinase activity |
| D | 0009025 | molecular_function | tagatose-bisphosphate aldolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019512 | biological_process | lactose catabolic process via tagatose-6-phosphate |
| D | 0061595 | molecular_function | 6-deoxy-6-sulfofructose-1-phosphate aldolase activity |
| D | 1902777 | biological_process | 6-sulfoquinovose(1-) catabolic process |
| D | 2001059 | biological_process | D-tagatose 6-phosphate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 13P A 3001 |
| Chain | Residue |
| A | ASP27 |
| A | GLY277 |
| A | ARG278 |
| A | HOH516 |
| A | GLN28 |
| A | LEU68 |
| A | LYS125 |
| A | GLU163 |
| A | LYS205 |
| A | SER249 |
| A | ALA250 |
| A | LEU275 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 327 |
| Chain | Residue |
| C | HOH346 |
| C | HOH352 |
| C | HOH397 |
| C | HOH413 |
| C | HOH414 |
| C | HOH446 |
| C | HOH1940 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 328 |
| Chain | Residue |
| A | HOH554 |
| A | HOH557 |
| A | HOH558 |
| A | HOH560 |
| A | HOH561 |
| A | HOH1835 |
| C | HOH379 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 329 |
| Chain | Residue |
| A | GLU238 |
| A | THR241 |
| A | HOH1268 |
| C | GLU83 |
| C | GLU84 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 13P B 3002 |
| Chain | Residue |
| B | ASP27 |
| B | GLN28 |
| B | LEU68 |
| B | LYS125 |
| B | GLU163 |
| B | LYS205 |
| B | LEU248 |
| B | SER249 |
| B | ALA250 |
| B | LEU275 |
| B | GLY277 |
| B | ARG278 |
| B | HOH1232 |
| B | HOH1565 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 327 |
| Chain | Residue |
| B | ASP259 |
| B | HOH893 |
| B | HOH1580 |
| B | HOH2129 |
| D | ASP259 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 13P C 3003 |
| Chain | Residue |
| C | ASP27 |
| C | GLN28 |
| C | LYS125 |
| C | GLU163 |
| C | LYS205 |
| C | LEU248 |
| C | SER249 |
| C | ALA250 |
| C | LEU275 |
| C | GLY277 |
| C | ARG278 |
| C | HOH738 |
| C | HOH1926 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 327 |
| Chain | Residue |
| A | GLU83 |
| A | GLU84 |
| C | GLU238 |
| C | THR241 |
| C | HOH1277 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA C 328 |
| Chain | Residue |
| C | ALA37 |
| C | GLN40 |
| C | HOH495 |
| C | HOH779 |
| C | HOH1812 |
| site_id | BC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 13P D 3004 |
| Chain | Residue |
| D | ALA25 |
| D | ASP27 |
| D | GLN28 |
| D | LEU68 |
| D | LYS125 |
| D | GLU163 |
| D | LYS205 |
| D | SER249 |
| D | ALA250 |
| D | LEU275 |
| D | GLY277 |
| D | ARG278 |
| D | HOH924 |
| D | HOH2410 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 327 |
| Chain | Residue |
| D | GLU84 |
| D | HOH959 |
| D | HOH1282 |
| D | HOH1820 |
| D | HOH2164 |
| D | HOH2165 |
