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3MGZ

Crystal structure of DHBPS domain of bi-functional DHBPS/GTP cyclohydrolase II from Mycobacterium tuberculosis at pH 4.0

Functional Information from GO Data
ChainGOidnamespacecontents
A0008686molecular_function3,4-dihydroxy-2-butanone-4-phosphate synthase activity
A0009231biological_processriboflavin biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 300
ChainResidue
AARG141
AGLY143
AHIS144
ATHR145
AHOH385

site_idAC2
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 301
ChainResidue
AARG140
AHOH320

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01283","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues2
DetailsSite: {"description":"Essential for DHBP synthase activity","evidences":[{"source":"HAMAP-Rule","id":"MF_01283","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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