3MCT

VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M3CYT AND S-ADENOSYLHOMOCYSTEINE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003746	molecular_function	translation elongation factor activity
A	0004483	molecular_function	methyltransferase cap1 activity
A	0006370	biological_process	7-methylguanosine mRNA capping
A	0031440	biological_process	regulation of mRNA 3'-end processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH A 400

Chain	Residue
A	GLN39
A	HIS74
A	ASP95
A	ARG97
A	PHE115
A	VAL116
A	ASP138
A	VAL139
A	ARG140
A	LEU42
A	TYR66
A	ILE67
A	GLY68
A	SER69
A	ALA70
A	PRO71
A	GLY72

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE 3MC A 600

Chain	Residue
A	TYR22
A	PHE180
A	TYR204
A	GLU233
A	HOH624

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	80
Details	Region: {"description":"Binding to NPH-I"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"For methyltransferase activity","evidences":[{"source":"PubMed","id":"15134442","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00944","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"8612277","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---