3MBQ

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, orthorhombic crystal form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004170	molecular_function	dUTP diphosphatase activity
A	0006226	biological_process	dUMP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046081	biological_process	dUTP catabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004170	molecular_function	dUTP diphosphatase activity
B	0006226	biological_process	dUMP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0046081	biological_process	dUTP catabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004170	molecular_function	dUTP diphosphatase activity
C	0006226	biological_process	dUMP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0046081	biological_process	dUTP catabolic process
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 201

Chain	Residue
A	ARG54
B	GLY110
B	ASP111
B	ASP112
B	HOH158

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 203

Chain	Residue
A	ARG38
A	ARG121
A	HOH158

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 201

Chain	Residue
B	HOH243
C	LYS82
C	GLY110
C	ASP111
C	ASP112
C	HOH225
B	ARG54

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	LYS82
A	GLY110
A	ASP111
A	ASP112
C	ARG54

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 203

Chain	Residue
C	ARG38
C	ARG121

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 206

Chain	Residue
C	ARG138
C	ALA139
C	LYS140

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 200

Chain	Residue
A	ASP23
A	ASP36
A	LEU37
A	ARG38
A	HOH207

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 202

Chain	Residue
A	ARG76
A	SER77
A	GLY78
A	ARG121

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 205

Chain	Residue
A	ILE73
A	CYS87
A	ASN89
A	LYS103
A	VAL104
A	LEU105
C	PHE151

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 200

Chain	Residue
B	ASP23
B	ASP36
B	LEU37
B	ARG38
B	HOH173

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 202

Chain	Residue
B	ARG76
B	SER77
B	GLY78
B	GLN124
B	HOH326
B	HOH329

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO B 205

Chain	Residue
B	ILE73
B	CYS87
B	ASN89
B	LYS103
B	VAL104
B	LEU105
B	HOH246

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO C 205

Chain	Residue
C	ILE73
C	CYS87
C	ASN89
C	LYS103
C	VAL104
C	LEU105

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 204

Chain	Residue
A	LEU16
A	GLU17
A	HIS18

---

site_id	BC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 202

Chain	Residue
C	ARG76
C	SER77
C	GLY78
C	GLN124
C	HOH217
C	HOH318
C	HOH319

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00116

Chain	Residue	Details
A	ARG76
C	ASN89
C	THR93
C	LYS103
A	ASN89
A	THR93
A	LYS103
B	ARG76
B	ASN89
B	THR93
B	LYS103
C	ARG76

---