3MBC
Crystal structure of monomeric isocitrate dehydrogenase from Corynebacterium glutamicum in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006097 | biological_process | glyoxylate cycle |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006097 | biological_process | glyoxylate cycle |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 739 |
| Chain | Residue |
| A | ASP346 |
| A | ASP544 |
| A | ASP548 |
| A | HOH1109 |
| A | HOH1110 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NAP A 740 |
| Chain | Residue |
| A | TRP597 |
| A | ASP598 |
| A | ARG645 |
| A | HOH1111 |
| A | HOH1251 |
| A | HOH1257 |
| A | HOH1302 |
| A | GLY579 |
| A | GLY580 |
| A | HIS585 |
| A | ARG596 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 739 |
| Chain | Residue |
| B | ASP346 |
| B | ASP544 |
| B | ASP548 |
| B | HOH832 |
| B | HOH833 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P16100","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16416443","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21931217","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2B0T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3MBC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21931217","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3MBC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
