3MAU

Crystal structure of StSPL in complex with phosphoethanolamine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
A	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
A	0016829	molecular_function	lyase activity
A	0016830	molecular_function	carbon-carbon lyase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0030149	biological_process	sphingolipid catabolic process
A	0030170	molecular_function	pyridoxal phosphate binding
A	0042802	molecular_function	identical protein binding
B	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
B	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
B	0016829	molecular_function	lyase activity
B	0016830	molecular_function	carbon-carbon lyase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0030149	biological_process	sphingolipid catabolic process
B	0030170	molecular_function	pyridoxal phosphate binding
B	0042802	molecular_function	identical protein binding
C	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
C	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
C	0016829	molecular_function	lyase activity
C	0016830	molecular_function	carbon-carbon lyase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0030149	biological_process	sphingolipid catabolic process
C	0030170	molecular_function	pyridoxal phosphate binding
C	0042802	molecular_function	identical protein binding
D	0004058	molecular_function	aromatic-L-amino-acid decarboxylase activity
D	0008117	molecular_function	sphinganine-1-phosphate aldolase activity
D	0016829	molecular_function	lyase activity
D	0016830	molecular_function	carbon-carbon lyase activity
D	0019752	biological_process	carboxylic acid metabolic process
D	0030149	biological_process	sphingolipid catabolic process
D	0030170	molecular_function	pyridoxal phosphate binding
D	0042802	molecular_function	identical protein binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PLR A 514

Chain	Residue
A	GLY168
A	HOH522
B	SER353
A	THR169
A	HIS201
A	TYR249
A	ASP274
A	CYS276
A	LEU277
A	ASP308
A	HIS310

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A 515

Chain	Residue
A	ALA103
A	TYR105
B	ASN126
B	HIS129

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site_id	AC3
Number of Residues	17
Details	BINDING SITE FOR RESIDUE EXT B 514

Chain	Residue
A	ASN126
A	LEU128
A	HIS129
A	GLY352
A	SER353
A	HOH526
B	ALA103
B	TYR105
B	GLY168
B	THR169
B	HIS201
B	TYR249
B	ASP274
B	LEU277
B	ASP308
B	HIS310
B	HOH516

---

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE EXT C 514

Chain	Residue
C	ALA103
C	TYR105
C	GLY168
C	THR169
C	HIS201
C	TYR249
C	ASP274
C	LEU277
C	ASP308
C	HIS310
D	ASN126
D	HIS129
D	SER353

---

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE EXT D 514

Chain	Residue
C	ASN126
C	HIS129
C	SER353
D	ALA103
D	TYR105
D	GLY168
D	THR169
D	HIS201
D	PRO247
D	TYR249
D	ASP274
D	LEU277
D	ASP308
D	HIS310

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