3M88
Crystal structure of the cysteine protease inhibitor, EhICP2, from Entamoeba histolytica
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004869 | molecular_function | cysteine-type endopeptidase inhibitor activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0010466 | biological_process | negative regulation of peptidase activity |
| A | 0019899 | molecular_function | enzyme binding |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0045335 | cellular_component | phagocytic vesicle |
| B | 0004869 | molecular_function | cysteine-type endopeptidase inhibitor activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0010466 | biological_process | negative regulation of peptidase activity |
| B | 0019899 | molecular_function | enzyme binding |
| B | 0031410 | cellular_component | cytoplasmic vesicle |
| B | 0045335 | cellular_component | phagocytic vesicle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1 |
| Chain | Residue |
| B | THR44 |
| B | TRP52 |
| B | ARG84 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 2 |
| Chain | Residue |
| A | HOH10 |
| A | THR44 |
| A | ALA51 |
| A | TRP52 |
| A | ARG84 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 124 |
| Chain | Residue |
| B | ARG104 |
| A | ARG104 |
