Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | ALA1 |
| A | HOH574 |
| A | ASN2 |
| A | ARG183 |
| A | PRO186 |
| A | HOH240 |
| A | HOH245 |
| A | HOH518 |
| A | HOH553 |
| A | HOH566 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | HIS36 |
| A | ARG140 |
| A | GLY141 |
| A | SER143 |
| A | HOH218 |
| A | HOH253 |
| A | HOH503 |
| A | HOH541 |
| A | HOH595 |
| A | HOH717 |
| B | LEU2184 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1003 |
| Chain | Residue |
| A | ALA27 |
| A | THR28 |
| A | ALA127 |
| A | ARG129 |
| A | HOH308 |
| A | HOH336 |
| A | HOH543 |
| A | HOH551 |
| A | HOH709 |
| A | HOH714 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1004 |
| Chain | Residue |
| A | ALA95 |
| A | VAL96 |
| A | LYS117 |
| A | HOH230 |
| A | HOH296 |
| A | HOH341 |
| A | HOH438 |
| A | HOH461 |
| A | HOH470 |
| A | HOH593 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAGHC |
| Chain | Residue | Details |
| A | VAL32-CYS37 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. CMgrGDSGGSWI |
| Chain | Residue | Details |
| A | CYS137-ILE148 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS36 | |
| A | ASP63 | |
| A | SER143 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 609 |
| Chain | Residue | Details |
| A | HIS36 | proton acceptor, proton donor |
| A | ASP63 | electrostatic stabiliser |
| A | GLY141 | electrostatic stabiliser |
| A | SER143 | electrostatic stabiliser |
| A | SER159 | electrostatic stabiliser |
