3M6F
CD11A I-domain complexed with 6-((5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL)-1-METHYL-2,4-DIOXO-1,3,7- TRIAZASPIRO[4.4]NON-7-YL)NICOTINIC ACID
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BJZ A 1 |
| Chain | Residue |
| A | TYR166 |
| A | HOH447 |
| A | THR231 |
| A | ILE235 |
| A | ILE255 |
| A | TYR257 |
| A | ILE259 |
| A | LYS287 |
| A | LEU302 |
| A | HOH408 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 A 401 |
| Chain | Residue |
| A | LYS276 |
| A | LYS280 |
| A | HOH444 |
| A | HOH460 |
| A | HOH491 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 171 |
| Details | Domain: {"description":"VWFA","evidences":[{"source":"PROSITE-ProRule","id":"PRU00219","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15728350","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1T0P","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26936951","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5E6R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5E6U","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
