3M4Z

Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004325	molecular_function	ferrochelatase activity
A	0005737	cellular_component	cytoplasm
A	0006783	biological_process	heme biosynthetic process
A	0016829	molecular_function	lyase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO A 310

Chain	Residue
A	HIS182
A	GLU263
A	HOH460
A	HOH514
A	HOH531
A	HOH532

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 311

Chain	Residue
A	HOH511
A	HOH512
A	HOH513
A	HOH424
A	HOH509
A	HOH510

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 312

Chain	Residue
A	HOH394
A	HOH453
A	HOH456
A	HOH459
A	HOH534
A	HOH535

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 313

Chain	Residue
A	GLU19
A	HOH536
A	HOH537
A	HOH538
A	HOH539
A	HOH540

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 314

Chain	Residue
A	ARG32
A	SER145
A	GLN198
A	HOH512

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 315

Chain	Residue
A	GLU144
A	LYS306

---

Functional Information from PROSITE/UniProt

site_id	PS00534
Number of Residues	19
Details	FERROCHELATASE Ferrochelatase signature. LIvSaHSLPekik.EfGDp...Y

Chain	Residue	Details
A	LEU177-TYR195

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10704318, ECO:0007744|PDB:1C1H

Chain	Residue	Details
A	TYR12
A	ARG30
A	HIS182
A	LYS187

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:17198378, ECO:0000305|PubMed:21052751

Chain	Residue	Details
A	GLU19

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00323

Chain	Residue	Details
A	ARG29
A	SER53
A	TYR124

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:12761666

Chain	Residue	Details
A	ARG45
A	ASP267
A	GLU271

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00323, ECO:0000305|PubMed:12761666, ECO:0000305|PubMed:16140324, ECO:0000305|PubMed:17198378, ECO:0000305|PubMed:21052751

Chain	Residue	Details
A	GLU263

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