3M4P
Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004816 | molecular_function | asparagine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006421 | biological_process | asparaginyl-tRNA aminoacylation |
| A | 0016874 | molecular_function | ligase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004816 | molecular_function | asparagine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006421 | biological_process | asparaginyl-tRNA aminoacylation |
| B | 0016874 | molecular_function | ligase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004816 | molecular_function | asparagine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006412 | biological_process | translation |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006421 | biological_process | asparaginyl-tRNA aminoacylation |
| C | 0016874 | molecular_function | ligase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004816 | molecular_function | asparagine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006412 | biological_process | translation |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006421 | biological_process | asparaginyl-tRNA aminoacylation |
| D | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 4AD A 500 |
| Chain | Residue |
| A | SER204 |
| A | GLU244 |
| A | TYR351 |
| A | GLU374 |
| A | ILE375 |
| A | VAL376 |
| A | GLY377 |
| A | ARG381 |
| A | TYR419 |
| A | GLY420 |
| A | GLY422 |
| A | GLN206 |
| A | ARG425 |
| A | ARG227 |
| A | GLU229 |
| A | ARG235 |
| A | HIS236 |
| A | LEU237 |
| A | TYR240 |
| A | HIS242 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 511 |
| Chain | Residue |
| A | PRO132 |
| A | MET135 |
| A | ARG232 |
| A | TYR445 |
| A | ARG448 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 512 |
| Chain | Residue |
| A | ILE131 |
| A | LYS134 |
| A | ARG437 |
| A | LYS438 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 513 |
| Chain | Residue |
| A | TYR35 |
| A | SER144 |
| A | GLU145 |
| A | HIS146 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 521 |
| Chain | Residue |
| A | ARG154 |
| A | GLU239 |
| A | TYR240 |
| A | LEU241 |
| A | GLU424 |
| A | CYS440 |
| A | LEU441 |
| B | GLN174 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 4AD B 500 |
| Chain | Residue |
| B | SER204 |
| B | GLN206 |
| B | ARG227 |
| B | ARG235 |
| B | HIS236 |
| B | LEU237 |
| B | TYR240 |
| B | HIS242 |
| B | GLU244 |
| B | TYR351 |
| B | GLU374 |
| B | ILE375 |
| B | GLY377 |
| B | ARG381 |
| B | TYR419 |
| B | GLY420 |
| B | GLY422 |
| B | ARG425 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 511 |
| Chain | Residue |
| B | ILE131 |
| B | PRO132 |
| B | MET135 |
| B | TYR445 |
| B | ARG448 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 512 |
| Chain | Residue |
| B | LYS134 |
| B | ARG437 |
| B | LYS438 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 513 |
| Chain | Residue |
| B | TYR35 |
| B | SER144 |
| B | GLU145 |
| B | HIS146 |
| site_id | BC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 4AD C 500 |
| Chain | Residue |
| C | SER204 |
| C | GLN206 |
| C | ARG227 |
| C | GLU229 |
| C | ARG235 |
| C | HIS236 |
| C | LEU237 |
| C | TYR240 |
| C | HIS242 |
| C | GLU244 |
| C | GLU374 |
| C | ILE375 |
| C | VAL376 |
| C | GLY377 |
| C | ARG381 |
| C | TYR419 |
| C | GLY420 |
| C | GLY422 |
| C | ARG425 |
| C | ILE436 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 511 |
| Chain | Residue |
| C | PRO132 |
| C | MET135 |
| C | TYR445 |
| C | GLU447 |
| C | ARG448 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 512 |
| Chain | Residue |
| C | LYS134 |
| C | ARG437 |
| C | LYS438 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 513 |
| Chain | Residue |
| C | TYR35 |
| C | SER144 |
| C | GLU145 |
| C | HIS146 |
| site_id | BC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 4AD D 500 |
| Chain | Residue |
| D | SER204 |
| D | GLN206 |
| D | ARG227 |
| D | ARG235 |
| D | HIS236 |
| D | LEU237 |
| D | TYR240 |
| D | HIS242 |
| D | GLU244 |
| D | TYR351 |
| D | GLU374 |
| D | ILE375 |
| D | ARG381 |
| D | TYR419 |
| D | GLY420 |
| D | LEU421 |
| D | GLY422 |
| D | ARG425 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 511 |
| Chain | Residue |
| B | HIS358 |
| D | PRO132 |
| D | MET135 |
| D | ARG232 |
| D | TYR445 |
| D | ARG448 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 512 |
| Chain | Residue |
| D | LYS134 |
| D | ARG437 |
| D | LYS438 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 513 |
| Chain | Residue |
| D | TYR35 |
| D | SER144 |
| D | GLU145 |
| D | HIS146 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 521 |
| Chain | Residue |
| C | GLN174 |
| D | ARG154 |
| D | GLU239 |
| D | GLU424 |
| D | TYR442 |
