3M0E

Crystal structure of the ATP-bound state of Walker B mutant of NtrC1 ATPase domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008134	molecular_function	transcription factor binding
A	0016887	molecular_function	ATP hydrolysis activity
B	0005524	molecular_function	ATP binding
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008134	molecular_function	transcription factor binding
B	0016887	molecular_function	ATP hydrolysis activity
C	0005524	molecular_function	ATP binding
C	0006355	biological_process	regulation of DNA-templated transcription
C	0008134	molecular_function	transcription factor binding
C	0016887	molecular_function	ATP hydrolysis activity
D	0005524	molecular_function	ATP binding
D	0006355	biological_process	regulation of DNA-templated transcription
D	0008134	molecular_function	transcription factor binding
D	0016887	molecular_function	ATP hydrolysis activity
E	0005524	molecular_function	ATP binding
E	0006355	biological_process	regulation of DNA-templated transcription
E	0008134	molecular_function	transcription factor binding
E	0016887	molecular_function	ATP hydrolysis activity
F	0005524	molecular_function	ATP binding
F	0006355	biological_process	regulation of DNA-templated transcription
F	0008134	molecular_function	transcription factor binding
F	0016887	molecular_function	ATP hydrolysis activity
G	0005524	molecular_function	ATP binding
G	0006355	biological_process	regulation of DNA-templated transcription
G	0008134	molecular_function	transcription factor binding
G	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP A 400

Chain	Residue
A	HOH16
A	LYS173
A	GLU174
A	VAL175
A	ASN280
A	LEU320
A	VAL356
A	ARG357
A	MG401
B	ASP295
B	ARG299
A	HOH49
A	HOH98
A	TYR139
A	VAL140
A	SER169
A	GLY170
A	VAL171
A	GLY172

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 401

Chain	Residue
A	HOH16
A	GLU174
A	ASP238
A	ATP400
A	HOH416

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ATP B 400

Chain	Residue
B	HOH14
B	HOH114
B	TYR139
B	VAL140
B	SER169
B	GLY170
B	VAL171
B	GLY172
B	LYS173
B	GLU174
B	VAL175
B	ASN280
B	VAL356
B	ARG357
B	MG401
B	HOH427
C	ASP295
C	ARG299

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	HOH14
B	GLU174
B	ATP400

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ATP C 400

Chain	Residue
C	HOH19
C	HOH43
C	TYR139
C	VAL140
C	SER169
C	GLY170
C	VAL171
C	GLY172
C	LYS173
C	GLU174
C	VAL175
C	ASN280
C	VAL356
C	ARG357
C	MG401
D	ASP295
D	ARG299

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 401

Chain	Residue
C	HOH19
C	GLU174
C	ASP238
C	ATP400

---

site_id	AC7
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ATP D 400

Chain	Residue
D	TYR139
D	VAL140
D	SER169
D	GLY170
D	VAL171
D	GLY172
D	LYS173
D	GLU174
D	VAL175
D	ASN280
D	LEU320
D	VAL356
D	ARG357
D	MG401
D	HOH410
E	HOH8
E	ASP295
E	ARG299

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 401

Chain	Residue
D	GLU174
D	ASP238
D	ATP400
E	HOH8

---

site_id	AC9
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP E 400

Chain	Residue
E	ASN280
E	LEU320
E	VAL356
E	ARG357
E	HOH395
E	MG401
F	ASP295
F	ARG299
E	HOH6
E	HOH68
E	TYR139
E	VAL140
E	SER169
E	GLY170
E	VAL171
E	GLY172
E	LYS173
E	GLU174
E	VAL175

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
E	HOH6
E	GLU174
E	ATP400
E	HOH405
F	ARG299

---

site_id	BC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ATP F 400

Chain	Residue
F	HOH18
F	HOH40
F	TYR139
F	VAL140
F	SER169
F	GLY170
F	VAL171
F	GLY172
F	LYS173
F	GLU174
F	VAL175
F	ASN280
F	VAL356
F	ARG357
F	MG401
G	ASP295
G	ARG299

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG F 401

Chain	Residue
F	HOH18
F	GLU174
F	ASP238
F	ATP400
F	HOH419

---

site_id	BC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ATP G 400

Chain	Residue
A	ASP295
A	ARG299
G	HOH7
G	HOH35
G	TYR139
G	VAL140
G	SER169
G	GLY170
G	VAL171
G	GLY172
G	LYS173
G	GLU174
G	VAL175
G	ASN280
G	LEU320
G	VAL356
G	ARG357
G	HOH388
G	MG401

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G 401

Chain	Residue
G	HOH7
G	GLU174
G	ASP238
G	ATP400
G	HOH422

---

Functional Information from PROSITE/UniProt

site_id	PS00675
Number of Residues	14
Details	SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VLItGESGVGKevV

Chain	Residue	Details
A	VAL163-VAL176

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