3LZT

REFINEMENT OF TRICLINIC LYSOZYME AT ATOMIC RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005794	cellular_component	Golgi apparatus
A	0016231	molecular_function	beta-N-acetylglucosaminidase activity
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium
A	0042802	molecular_function	identical protein binding
A	0050829	biological_process	defense response to Gram-negative bacterium
A	0050830	biological_process	defense response to Gram-positive bacterium
A	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 A 150

Chain	Residue
A	ARG14
A	LYS33
A	ASN37
A	TRP62
A	ARG73
A	HOH2280
A	HOH2292

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 A 151

Chain	Residue
A	ARG73
A	TRP123
A	HOH2077
A	HOH2323
A	LYS33
A	PHE38

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 152

Chain	Residue
A	ARG21
A	GLY22
A	ASN65
A	ASP66
A	PRO79
A	CYS80
A	SER81
A	HOH2078

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 153

Chain	Residue
A	TYR23
A	ARG45
A	GLY104
A	MET105
A	ASN106
A	TRP111
A	HOH2109
A	HOH2124

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 A 154

Chain	Residue
A	ASN65
A	ASN74
A	ASN77
A	ILE78
A	PRO79
A	ARG112
A	LYS116

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO3 A 155

Chain	Residue
A	ALA11
A	ARG14
A	HIS15
A	ASP87
A	ILE88
A	HOH2094
A	HOH2113

---

site_id	AC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ACT A 201

Chain	Residue
A	TYR20
A	ARG21
A	ALA110
A	ASN113
A	ARG114
A	ARG128
A	HOH2044
A	HOH2078
A	HOH2118
A	HOH2123
A	HOH2137
A	HOH2333
A	HOH2334

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACT A 203

Chain	Residue
A	ILE58
A	ASN59
A	TRP63
A	ALA107
A	TRP108
A	HOH2085
A	HOH2127
A	HOH2179
A	HOH2202

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT A 204

Chain	Residue
A	ASN46
A	THR47
A	ASP48
A	LYS97
A	HOH2027
A	HOH2090
A	HOH2185
A	HOH2188

---

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
A	CYS76-CYS94

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	128
Details	Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
A	GLU35
A	ASP52

---

site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
A	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ASN46
A	ASP48
A	SER50
A	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
A	ASN59

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