Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3LW2

Mouse Plasminogen Activator Inhibitor-1 (PAI-1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0001890biological_processplacenta development
A0002020molecular_functionprotease binding
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0008585biological_processfemale gonad development
A0010628biological_processpositive regulation of gene expression
A0010629biological_processnegative regulation of gene expression
A0010757biological_processnegative regulation of plasminogen activation
A0030336biological_processnegative regulation of cell migration
A0032967biological_processpositive regulation of collagen biosynthetic process
A0042127biological_processregulation of cell population proliferation
A0042583cellular_componentchromaffin granule
A0045765biological_processregulation of angiogenesis
A0045766biological_processpositive regulation of angiogenesis
A0048146biological_processpositive regulation of fibroblast proliferation
A0048260biological_processpositive regulation of receptor-mediated endocytosis
A0050820biological_processpositive regulation of coagulation
A0050829biological_processdefense response to Gram-negative bacterium
A0051549biological_processpositive regulation of keratinocyte migration
A0051918biological_processnegative regulation of fibrinolysis
A0061044biological_processnegative regulation of vascular wound healing
A0062023cellular_componentcollagen-containing extracellular matrix
A0071347biological_processcellular response to interleukin-1
A0071466biological_processcellular response to xenobiotic stimulus
A0071560biological_processcellular response to transforming growth factor beta stimulus
A0090280biological_processpositive regulation of calcium ion import
A0097180cellular_componentserine protease inhibitor complex
A1904090cellular_componentpeptidase inhibitor complex
A1905043biological_processpositive regulation of epithelium regeneration
Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. MVIDRSFLFvV
ChainResidueDetails
AMET352-VAL362

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Reactive bond
ChainResidueDetails
AARG346

site_idSWS_FT_FI2
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN209
AASN265
AASN329

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon