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3LW2

Mouse Plasminogen Activator Inhibitor-1 (PAI-1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0001525biological_processangiogenesis
A0001890biological_processplacenta development
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0009617biological_processresponse to bacterium
A0010757biological_processnegative regulation of plasminogen activation
A0030414molecular_functionpeptidase inhibitor activity
A0042127biological_processregulation of cell population proliferation
A0045765biological_processregulation of angiogenesis
A0045766biological_processpositive regulation of angiogenesis
A0050820biological_processpositive regulation of coagulation
A0050829biological_processdefense response to Gram-negative bacterium
A0051918biological_processnegative regulation of fibrinolysis
A0061044biological_processnegative regulation of vascular wound healing
A0061045biological_processnegative regulation of wound healing
A0071560biological_processcellular response to transforming growth factor beta stimulus
A0097180cellular_componentserine protease inhibitor complex
A1904090cellular_componentpeptidase inhibitor complex
Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. MVIDRSFLFvV
ChainResidueDetails
AMET352-VAL362

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsSITE: Reactive bond
ChainResidueDetails
AARG346

site_idSWS_FT_FI2
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN209
AASN265
AASN329

237735

PDB entries from 2025-06-18

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