3LUB
Crystal structure of Putative creatinine amidohydrolase (YP_211512.1) from Bacteroides fragilis NCTC 9343 at 2.11 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047789 | molecular_function | creatininase activity |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047789 | molecular_function | creatininase activity |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0047789 | molecular_function | creatininase activity |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0047789 | molecular_function | creatininase activity |
| E | 0009231 | biological_process | riboflavin biosynthetic process |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0047789 | molecular_function | creatininase activity |
| F | 0009231 | biological_process | riboflavin biosynthetic process |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0047789 | molecular_function | creatininase activity |
| G | 0009231 | biological_process | riboflavin biosynthetic process |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0047789 | molecular_function | creatininase activity |
| H | 0009231 | biological_process | riboflavin biosynthetic process |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0047789 | molecular_function | creatininase activity |
| I | 0009231 | biological_process | riboflavin biosynthetic process |
| I | 0016787 | molecular_function | hydrolase activity |
| I | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| I | 0046872 | molecular_function | metal ion binding |
| I | 0047789 | molecular_function | creatininase activity |
| J | 0009231 | biological_process | riboflavin biosynthetic process |
| J | 0016787 | molecular_function | hydrolase activity |
| J | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| J | 0046872 | molecular_function | metal ion binding |
| J | 0047789 | molecular_function | creatininase activity |
| K | 0009231 | biological_process | riboflavin biosynthetic process |
| K | 0016787 | molecular_function | hydrolase activity |
| K | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| K | 0046872 | molecular_function | metal ion binding |
| K | 0047789 | molecular_function | creatininase activity |
| L | 0009231 | biological_process | riboflavin biosynthetic process |
| L | 0016787 | molecular_function | hydrolase activity |
| L | 0016811 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
| L | 0046872 | molecular_function | metal ion binding |
| L | 0047789 | molecular_function | creatininase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | GLU31 |
| A | ASP42 |
| A | HIS119 |
| A | ZN302 |
| A | HOH454 |
| A | HOH775 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 302 |
| Chain | Residue |
| A | ZN301 |
| A | HOH775 |
| A | HIS33 |
| A | ASP42 |
| A | GLU167 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 254 |
| Chain | Residue |
| A | HOH434 |
| A | HOH1795 |
| A | HOH1920 |
| F | HOH1824 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 255 |
| Chain | Residue |
| A | ASN77 |
| A | ARG206 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 301 |
| Chain | Residue |
| B | GLU31 |
| B | ASP42 |
| B | HIS119 |
| B | HOH262 |
| B | ZN302 |
| B | HOH1005 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 302 |
| Chain | Residue |
| B | HIS33 |
| B | ASP42 |
| B | GLU167 |
| B | HOH262 |
| B | ZN301 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 254 |
| Chain | Residue |
| A | THR30 |
| A | PRO72 |
| B | LEU25 |
| B | MSE68 |
| B | PRO69 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 255 |
| Chain | Residue |
| B | ASN77 |
| B | ARG206 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN C 301 |
| Chain | Residue |
| C | GLU31 |
| C | ASP42 |
| C | HIS119 |
| C | ZN302 |
| C | HOH332 |
| C | HOH478 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 302 |
| Chain | Residue |
| C | HIS33 |
| C | ASP42 |
| C | GLU167 |
| C | ZN301 |
| C | HOH332 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 254 |
| Chain | Residue |
| B | HOH2105 |
| C | HOH290 |
| C | HOH597 |
| C | HOH873 |
| C | HOH1850 |
| C | HOH1942 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 255 |
| Chain | Residue |
| C | GLY79 |
| C | GLN80 |
| C | ARG81 |
| C | GLU82 |
| C | HOH1352 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 256 |
| Chain | Residue |
| C | LEU25 |
| C | MSE68 |
| C | PRO69 |
| D | THR30 |
| D | PRO72 |
| D | PHE73 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 257 |
| Chain | Residue |
| C | ASN77 |
| C | ARG206 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN D 301 |
| Chain | Residue |
| D | GLU31 |
| D | ASP42 |
| D | HIS119 |
| D | HOH289 |
| D | HOH292 |
| D | HOH295 |
| D | ZN302 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 302 |
| Chain | Residue |
| D | HIS33 |
| D | ASP42 |
| D | GLU167 |
| D | HOH289 |
| D | ZN301 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 254 |
| Chain | Residue |
| D | ASP209 |
| D | HOH1119 |
| D | HOH1188 |
| D | HOH1204 |
| D | HOH1232 |
| D | HOH1752 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA D 255 |
| Chain | Residue |
| D | HOH1045 |
| D | HOH1809 |
| D | HOH2150 |
| E | HOH270 |
| E | HOH1781 |
| E | HOH2143 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 256 |
| Chain | Residue |
| D | SER103 |
| D | HIS106 |
| D | VAL107 |
| D | TYR135 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 257 |
| Chain | Residue |
| C | VAL107 |
| D | GLY79 |
| D | ARG81 |
| D | GLU82 |
| D | HOH1178 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 258 |
| Chain | Residue |
| D | ARG206 |
| D | ASN77 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN E 301 |
| Chain | Residue |
| E | GLU31 |
| E | ASP42 |
| E | HIS119 |
| E | ZN302 |
| E | HOH333 |
| E | HOH445 |
| E | HOH1163 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN E 302 |
| Chain | Residue |
| E | HIS33 |
| E | ASP42 |
| E | GLU167 |
| E | ZN301 |
| E | HOH445 |
| site_id | CC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 254 |
| Chain | Residue |
| E | ASP209 |
| E | HOH887 |
| E | HOH1371 |
| E | HOH1525 |
| E | HOH1669 |
| E | HOH1957 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA E 255 |
| Chain | Residue |
| D | HOH283 |
| D | HOH1736 |
| E | HOH999 |
| E | HOH1249 |
| E | HOH1533 |
| E | HOH1756 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 256 |
| Chain | Residue |
| E | LEU25 |
| E | MSE68 |
| E | PRO69 |
| F | THR30 |
| F | PHE73 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL E 257 |
| Chain | Residue |
| E | GLY79 |
| E | ARG81 |
| E | GLU82 |
| E | HOH841 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL E 258 |
| Chain | Residue |
| E | ASN77 |
| E | ARG206 |
| site_id | DC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN F 301 |
| Chain | Residue |
| F | GLU31 |
| F | ASP42 |
| F | HIS119 |
| F | ZN302 |
| F | HOH560 |
| F | HOH1337 |
| site_id | DC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN F 302 |
| Chain | Residue |
| F | HIS33 |
| F | ASP42 |
| F | GLU167 |
| F | ZN301 |
| F | HOH560 |
| site_id | DC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA F 254 |
| Chain | Residue |
| F | HOH581 |
| F | HOH883 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL F 255 |
| Chain | Residue |
| F | ASN77 |
| F | ARG206 |
| site_id | DC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN G 301 |
| Chain | Residue |
| G | GLU31 |
| G | ASP42 |
| G | HIS119 |
| G | ZN302 |
| G | HOH380 |
| G | HOH613 |
| G | HOH754 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN G 302 |
| Chain | Residue |
| G | HIS33 |
| G | ASP42 |
| G | GLU167 |
| G | ZN301 |
| G | HOH380 |
| site_id | DC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA G 254 |
| Chain | Residue |
| G | HOH1037 |
| G | HOH1326 |
| G | HOH2063 |
| G | HOH2098 |
| L | HOH377 |
| L | HOH1567 |
| L | HOH1822 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO G 255 |
| Chain | Residue |
| G | LEU25 |
| G | MSE68 |
| G | PRO69 |
| H | THR30 |
| H | PRO72 |
| H | PHE73 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL G 256 |
| Chain | Residue |
| G | ASN77 |
| G | ARG206 |
| site_id | EC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ZN H 301 |
| Chain | Residue |
| H | GLU31 |
| H | ASP42 |
| H | HIS119 |
| H | HOH268 |
| H | ZN302 |
| H | HOH486 |
| H | HOH1257 |
| site_id | EC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN H 302 |
| Chain | Residue |
| H | HIS33 |
| H | ASP42 |
| H | GLU167 |
| H | HOH268 |
| H | ZN301 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL H 254 |
| Chain | Residue |
| H | ASN77 |
| H | ARG206 |
| site_id | EC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN I 301 |
| Chain | Residue |
| I | GLU31 |
| I | ASP42 |
| I | HIS119 |
| I | ZN302 |
| I | HOH462 |
| I | HOH508 |
| site_id | EC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN I 302 |
| Chain | Residue |
| I | HIS33 |
| I | ASP42 |
| I | GLU167 |
| I | ZN301 |
| I | HOH462 |
| site_id | EC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA I 254 |
| Chain | Residue |
| I | ASP209 |
| I | HOH477 |
| I | HOH506 |
| I | HOH698 |
| I | HOH1055 |
| I | HOH1420 |
| I | HOH1560 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA I 255 |
| Chain | Residue |
| I | HOH260 |
| I | HOH1208 |
| I | HOH1476 |
| I | HOH1981 |
| I | HOH2104 |
| site_id | EC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL I 256 |
| Chain | Residue |
| I | ASN77 |
| I | ARG206 |
| site_id | FC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN J 301 |
| Chain | Residue |
| J | GLU31 |
| J | ASP42 |
| J | HIS119 |
| J | HOH270 |
| J | ZN302 |
| J | HOH1099 |
| site_id | FC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN J 302 |
| Chain | Residue |
| J | HIS33 |
| J | ASP42 |
| J | GLU167 |
| J | HOH270 |
| J | ZN301 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA J 254 |
| Chain | Residue |
| J | HOH291 |
| J | HOH605 |
| J | HOH1568 |
| J | HOH1667 |
| J | HOH1881 |
| J | HOH1938 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO J 255 |
| Chain | Residue |
| I | THR30 |
| I | PHE73 |
| J | LEU25 |
| J | PRO69 |
| J | ILE101 |
| site_id | FC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL J 256 |
| Chain | Residue |
| J | ASN77 |
| J | ARG206 |
| site_id | FC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN K 301 |
| Chain | Residue |
| K | GLU31 |
| K | ASP42 |
| K | HIS119 |
| K | ZN302 |
| K | HOH524 |
| K | HOH549 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN K 302 |
| Chain | Residue |
| K | HIS33 |
| K | ASP42 |
| K | GLU167 |
| K | ZN301 |
| K | HOH549 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO K 254 |
| Chain | Residue |
| K | LEU25 |
| K | MSE68 |
| K | PRO69 |
| L | THR30 |
| L | PRO72 |
| L | PHE73 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO K 255 |
| Chain | Residue |
| K | GLY79 |
| K | ARG81 |
| K | GLU82 |
| site_id | GC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL K 256 |
| Chain | Residue |
| K | ASN77 |
| K | ARG206 |
| site_id | GC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN L 301 |
| Chain | Residue |
| L | GLU31 |
| L | ASP42 |
| L | HIS119 |
| L | ZN302 |
| L | HOH453 |
| L | HOH1225 |
| site_id | GC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN L 302 |
| Chain | Residue |
| L | HIS33 |
| L | ASP42 |
| L | GLU167 |
| L | ZN301 |
| L | HOH453 |
| site_id | GC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA L 254 |
| Chain | Residue |
| L | HOH321 |
| L | HOH1472 |
| L | HOH1622 |
| site_id | GC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO L 255 |
| Chain | Residue |
| K | THR30 |
| K | PHE73 |
| L | LEU25 |
| L | MSE68 |
| L | PRO69 |
| site_id | GC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL L 256 |
| Chain | Residue |
| L | ASN77 |
| L | ARG206 |
