3LTO
Crystal structure of a mevalonate diphosphate decarboxylase from Legionella pneumophila
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| B | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | ALA20 |
| A | LYS23 |
| A | TYR24 |
| A | MSE25 |
| A | SER157 |
| A | ARG160 |
| A | ASP291 |
| A | HOH386 |
| A | HOH393 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | TYR24 |
| A | GLY26 |
| A | LYS28 |
| A | ARG152 |
| A | SER155 |
| A | GLY156 |
| A | ARG201 |
| A | HOH361 |
| A | HOH389 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | SER77 |
| A | VAL78 |
| A | GLU79 |
| A | HOH377 |
| B | GLU276 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 403 |
| Chain | Residue |
| A | GLU276 |
| B | VAL78 |
| B | GLU79 |
| B | HOH336 |
| B | HOH345 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 404 |
| Chain | Residue |
| B | TYR24 |
| B | GLY26 |
| B | LYS28 |
| B | ARG152 |
| B | SER155 |
| B | GLY156 |
| B | ARG201 |
| B | HOH383 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 405 |
| Chain | Residue |
| B | ALA20 |
| B | LYS23 |
| B | TYR24 |
| B | MSE25 |
| B | SER157 |
| B | ARG160 |
| B | HOH357 |
| B | HOH366 |
