3LSW

Aniracetam bound to the ligand binding domain of GluA3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE GLU A 400

Chain	Residue
A	TYR61
A	GLU193
A	HOH352
A	HOH356
A	HOH365
A	PRO89
A	LEU90
A	THR91
A	ARG96
A	LEU138
A	GLY141
A	SER142
A	THR143

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site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE 4MP A 801

Chain	Residue
A	PRO105
A	PRO105
A	MET107
A	MET107
A	SER108
A	SER108
A	SER217
A	SER217
A	LYS218
A	LYS218
A	GLY219
A	GLY219
A	HOH290
A	HOH290
A	HOH323
A	HOH323

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 1

Chain	Residue
A	HIS23
A	GLU24
A	HOH291

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ZN A 2

Chain	Residue
A	GLU42
A	HIS46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20163115","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LSW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LSX","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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