3LST
Crystal Structure of CalO1, Methyltransferase in Calicheamicin Biosynthesis, SAH bound form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0046983 | molecular_function | protein dimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE SAH A 346 |
| Chain | Residue |
| A | SER166 |
| A | ARG252 |
| A | ILE253 |
| A | TRP257 |
| A | HOH359 |
| A | HOH390 |
| A | GLY189 |
| A | GLY190 |
| A | ASP212 |
| A | ARG213 |
| A | VAL216 |
| A | ASP237 |
| A | PHE238 |
| A | LYS251 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 347 |
| Chain | Residue |
| A | GLU26 |
| A | TYR32 |
| A | ARG79 |
| A | HOH381 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SAH B 346 |
| Chain | Residue |
| B | GLY189 |
| B | ASP212 |
| B | ARG213 |
| B | VAL216 |
| B | GLY236 |
| B | ASP237 |
| B | PHE238 |
| B | LYS251 |
| B | ARG252 |
| B | ILE253 |
| B | TRP257 |
| B | HOH354 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 347 |
| Chain | Residue |
| B | GLU26 |
| B | GLY29 |
| B | TYR32 |
| B | ARG79 |
