3LRJ
Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate synthase in complex with sulfate ion.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0008686 | molecular_function | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0008686 | molecular_function | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0008686 | molecular_function | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0030145 | molecular_function | manganese ion binding |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0008686 | molecular_function | 3,4-dihydroxy-2-butanone-4-phosphate synthase activity |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0030145 | molecular_function | manganese ion binding |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | THR93 |
| A | ARG150 |
| A | GLY152 |
| A | HIS153 |
| A | THR154 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ALA190 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | THR154 |
| B | ARG150 |
| B | GLY152 |
| B | HIS153 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 300 |
| Chain | Residue |
| C | THR93 |
| C | ARG150 |
| C | GLY152 |
| C | HIS153 |
| C | THR154 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 305 |
| Chain | Residue |
| A | GLU85 |
| C | GLU72 |
| C | ARG141 |
| C | GLN143 |
| C | ALA144 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | GLU38 |
| D | THR93 |
| D | ARG150 |
| D | GLY152 |
| D | HIS153 |
| D | THR154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00180 |
| Chain | Residue | Details |
| A | ARG37 | |
| B | ARG150 | |
| B | HIS153 | |
| B | GLU174 | |
| C | ARG37 | |
| C | GLU38 | |
| C | ASP42 | |
| C | ARG150 | |
| C | HIS153 | |
| C | GLU174 | |
| D | ARG37 | |
| A | GLU38 | |
| D | GLU38 | |
| D | ASP42 | |
| D | ARG150 | |
| D | HIS153 | |
| D | GLU174 | |
| A | ASP42 | |
| A | ARG150 | |
| A | HIS153 | |
| A | GLU174 | |
| B | ARG37 | |
| B | GLU38 | |
| B | ASP42 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | SITE: Essential for catalytic activity => ECO:0000255|HAMAP-Rule:MF_00180 |
| Chain | Residue | Details |
| A | HIS136 | |
| A | GLU174 | |
| B | HIS136 | |
| B | GLU174 | |
| C | HIS136 | |
| C | GLU174 | |
| D | HIS136 | |
| D | GLU174 |
