Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042800 | molecular_function | histone methyltransferase activity (H3-K4 specific) |
| A | 0071339 | cellular_component | MLL1 complex |
| B | 0042800 | molecular_function | histone methyltransferase activity (H3-K4 specific) |
| B | 0071339 | cellular_component | MLL1 complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 3 |
| Chain | Residue |
| A | CYS1569 |
| A | CYS1572 |
| A | HIS1596 |
| A | CYS1599 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4 |
| Chain | Residue |
| A | CYS1588 |
| A | CYS1591 |
| A | CYS1621 |
| A | CYS1624 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1 |
| Chain | Residue |
| B | CYS1572 |
| B | HIS1596 |
| B | CYS1599 |
| B | CYS1569 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 2 |
| Chain | Residue |
| B | CYS1588 |
| B | CYS1591 |
| B | CYS1621 |
| B | CYS1624 |
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 56 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. CplCdkcyddddyeskm................................MqCgk..Cdrw.VHskCenlsdemyeilsnlpesva..........................YtCvnC |
| Chain | Residue | Details |
| A | CYS1569-CYS1624 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 122 |
| Details | Zinc finger: {"description":"PHD-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Region: {"description":"Interaction with histone H3K4me3","evidences":[{"source":"PubMed","id":"20677832","evidenceCode":"ECO:0000269"}]} |
