3LP6
Crystal Structure of Rv3275c-E60A from Mycobacterium tuberculosis at 1.7A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0034023 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide mutase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006164 | biological_process | purine nucleotide biosynthetic process |
| B | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0034023 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide mutase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006164 | biological_process | purine nucleotide biosynthetic process |
| C | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0034023 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide mutase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006164 | biological_process | purine nucleotide biosynthetic process |
| D | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0034023 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide mutase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 175 |
| Chain | Residue |
| A | ASP19 |
| A | GLY71 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 176 |
| Chain | Residue |
| A | ARG56 |
| A | ALA82 |
| C | HOH325 |
| D | FMT175 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 177 |
| Chain | Residue |
| A | HIS45 |
| A | ARG46 |
| A | HOH188 |
| A | HOH400 |
| A | GLY15 |
| A | SER43 |
| A | ALA44 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT A 178 |
| Chain | Residue |
| A | THR47 |
| A | PRO48 |
| A | GLU49 |
| A | ALA50 |
| A | HOH224 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 175 |
| Chain | Residue |
| B | GLY15 |
| B | ASP19 |
| B | ALA70 |
| B | GLY71 |
| B | LEU95 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 176 |
| Chain | Residue |
| B | FMT178 |
| C | THR47 |
| C | PRO48 |
| C | GLU49 |
| C | ALA50 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 177 |
| Chain | Residue |
| B | THR47 |
| B | PRO48 |
| B | GLU49 |
| B | ALA50 |
| C | GOL175 |
| C | HOH238 |
| C | HOH355 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 178 |
| Chain | Residue |
| B | ARG56 |
| B | ALA82 |
| B | FMT176 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT B 179 |
| Chain | Residue |
| B | VAL41 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 180 |
| Chain | Residue |
| B | GLY15 |
| B | SER43 |
| B | ALA44 |
| B | HIS45 |
| B | ARG46 |
| B | FMT182 |
| B | HOH187 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 181 |
| Chain | Residue |
| A | LYS160 |
| B | SER16 |
| B | ASP17 |
| B | ARG46 |
| B | HOH349 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 182 |
| Chain | Residue |
| B | HIS45 |
| B | ARG46 |
| B | FMT180 |
| B | HOH209 |
| C | PRO111 |
| C | HOH211 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL C 175 |
| Chain | Residue |
| A | GLN150 |
| A | ASP151 |
| A | HOH192 |
| A | HOH285 |
| B | PRO48 |
| B | FMT177 |
| C | ARG56 |
| C | ALA82 |
| C | ALA83 |
| C | HOH204 |
| C | HOH332 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT C 176 |
| Chain | Residue |
| C | ASP19 |
| C | ALA70 |
| C | GLY71 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT C 177 |
| Chain | Residue |
| C | GLU32 |
| C | PHE33 |
| C | ARG145 |
| C | ARG152 |
| C | HOH209 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT C 178 |
| Chain | Residue |
| B | LYS160 |
| C | SER16 |
| C | ASP17 |
| C | ARG46 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT C 179 |
| Chain | Residue |
| C | GLY15 |
| C | SER43 |
| C | ALA44 |
| C | HIS45 |
| C | HOH193 |
| C | HOH407 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT D 175 |
| Chain | Residue |
| A | FMT176 |
| D | THR47 |
| D | PRO48 |
| D | GLU49 |
| D | ALA50 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT D 176 |
| Chain | Residue |
| D | GLY15 |
| D | SER43 |
| D | ALA44 |
| D | HIS45 |
| D | HOH202 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT D 177 |
| Chain | Residue |
| A | VAL41 |
| A | HOH323 |
| D | HOH329 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT D 178 |
| Chain | Residue |
| A | HIS45 |
| A | HOH210 |
| D | ALA82 |
| D | GLN150 |
| D | HOH243 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT D 179 |
| Chain | Residue |
| D | ASP19 |
| D | GLY71 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT D 180 |
| Chain | Residue |
| D | GLU32 |
| D | ARG145 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT D 181 |
| Chain | Residue |
| D | GLY5 |
| D | HOH233 |
| D | HOH408 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01929","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
