3LOX
HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0006508 | biological_process | proteolysis |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0019087 | biological_process | transformation of host cell by virus |
C | 0006508 | biological_process | proteolysis |
C | 0008236 | molecular_function | serine-type peptidase activity |
C | 0019087 | biological_process | transformation of host cell by virus |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 901 |
Chain | Residue |
A | CYS97 |
A | CYS99 |
A | CYS145 |
A | HOH199 |
site_id | AC2 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE MCX A 999 |
Chain | Residue |
A | SER139 |
A | PHE154 |
A | ARG155 |
A | ALA156 |
A | ALA157 |
A | ASP168 |
A | HIS57 |
A | ARG123 |
A | ILE132 |
A | GLY137 |
A | SER138 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE BME A 998 |
Chain | Residue |
A | LEU13 |
A | CYS16 |
A | ILE17 |
A | THR38 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN C 902 |
Chain | Residue |
C | CYS97 |
C | CYS99 |
C | CYS145 |
C | HOH191 |