3LON
HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0019087 | biological_process | transformation of host cell by virus |
| C | 0006508 | biological_process | proteolysis |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0019087 | biological_process | transformation of host cell by virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 901 |
| Chain | Residue |
| A | CYS97 |
| A | CYS99 |
| A | CYS145 |
| A | HOH190 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NNA A 999 |
| Chain | Residue |
| A | LYS136 |
| A | GLY137 |
| A | SER138 |
| A | SER139 |
| A | ARG155 |
| A | ALA156 |
| A | ALA157 |
| A | VAL158 |
| A | CYS159 |
| A | ASP168 |
| A | HOH202 |
| A | GLN41 |
| A | THR42 |
| A | HIS57 |
| A | ARG123 |
| A | ILE132 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BME A 998 |
| Chain | Residue |
| A | LEU13 |
| A | CYS16 |
| A | ILE17 |
| A | THR38 |
| A | ALA39 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 902 |
| Chain | Residue |
| C | CYS97 |
| C | CYS99 |
| C | CYS145 |
| C | HOH190 |
