3LOE

Crystal structure of human alpha-defensin 1 (F28A mutant)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0006952	biological_process	defense response

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 31

Chain	Residue
A	ALA8
A	CYS9
A	ARG14
A	ARG15
A	ARG24
A	HOH46
A	HOH47
A	HOH49

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 32

Chain	Residue
A	ARG15
A	LEU25
A	TRP26
A	ALA27
A	HOH69
A	PRO7

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Functional Information from PROSITE/UniProt

site_id	PS00269
Number of Residues	29
Details	DEFENSIN Mammalian defensins signature. CyCripa.CiagerryGtCiyqgrlwaaCC

Chain	Residue	Details
A	CYS2-CYS30

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Peptide: {"description":"Neutrophil defensin 1","featureId":"PRO_0000006773"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	28
Details	Peptide: {"description":"Neutrophil defensin 2","featureId":"PRO_0000006774"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"ADP-ribosylarginine; by ART1","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"21904558","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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