Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 264 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | HAE301 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 265 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 266 |
| Chain | Residue |
| A | HOH54 |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH5 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 267 |
| Chain | Residue |
| A | HOH12 |
| A | HOH21 |
| A | ASP124 |
| A | GLU199 |
| A | GLU201 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 268 |
| Chain | Residue |
| A | ASP175 |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HAE A 301 |
| Chain | Residue |
| A | HOH1 |
| A | HOH91 |
| A | ILE180 |
| A | ALA182 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| A | HIS228 |
| A | ZN264 |
| A | EEF302 |
| A | HOH340 |
| A | HOH393 |
| A | HOH480 |
| site_id | AC7 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE EEF A 302 |
| Chain | Residue |
| A | HOH78 |
| A | THR154 |
| A | GLY155 |
| A | GLY179 |
| A | LEU181 |
| A | HIS218 |
| A | GLU219 |
| A | PRO232 |
| A | VAL235 |
| A | PHE237 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | LYS241 |
| A | HOH281 |
| A | HOH288 |
| A | HAE301 |
| A | HOH333 |
| A | HOH377 |
| A | HOH401 |
| A | HOH412 |
| A | HOH415 |
| A | HOH493 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE P6G A 304 |
| Chain | Residue |
| A | HIS228 |
| A | SER229 |
| A | SER230 |
| A | PRO238 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE P6G A 305 |
| Chain | Residue |
| A | HOH89 |
| A | TRP109 |
| A | ARG110 |
| A | ASN126 |
| A | ASP129 |
| A | GLY188 |
| A | SER189 |
| A | HOH291 |
| A | HOH348 |
| A | HOH394 |
| A | HOH437 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU219 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 19 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP124 | |
| A | GLY190 | |
| A | GLY192 | |
| A | ASP194 | |
| A | HIS196 | |
| A | ASP198 | |
| A | GLU199 | |
| A | GLU201 | |
| A | HIS218 | |
| A | HIS222 | |
| A | HIS228 | |
| A | ASP158 | |
| A | HIS168 | |
| A | ASP170 | |
| A | ASP175 | |
| A | GLY176 | |
| A | GLY178 | |
| A | ILE180 | |
| A | HIS183 | |
