Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006397 | biological_process | mRNA processing |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0030968 | biological_process | endoplasmic reticulum unfolded protein response |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004674 | molecular_function | protein serine/threonine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006397 | biological_process | mRNA processing |
| B | 0006468 | biological_process | protein phosphorylation |
| B | 0030968 | biological_process | endoplasmic reticulum unfolded protein response |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IZA A 1 |
| Chain | Residue |
| A | LEU680 |
| A | LEU804 |
| A | ASP828 |
| A | TYR682 |
| A | ALA700 |
| A | GLU746 |
| A | LEU747 |
| A | CYS748 |
| A | ASN749 |
| A | LEU750 |
| A | GLN801 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE IZA B 1 |
| Chain | Residue |
| B | LEU680 |
| B | TYR682 |
| B | VAL689 |
| B | ALA700 |
| B | GLU746 |
| B | LEU747 |
| B | CYS748 |
| B | ASN749 |
| B | LEU750 |
| B | GLN801 |
| B | LEU804 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpqNILV |
| Chain | Residue | Details |
| A | ILE793-VAL805 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP797 | |
| B | ASP797 | |
| Chain | Residue | Details |
| A | SER684 | |
| B | GLU746 | |
| B | CYS748 | |
| B | ASN751 | |
| B | ASN802 | |
| B | ASP828 | |
| A | LYS702 | |
| A | GLU746 | |
| A | CYS748 | |
| A | ASN751 | |
| A | ASN802 | |
| A | ASP828 | |
| B | SER684 | |
| B | LYS702 | |
| Chain | Residue | Details |
| A | SEP840 | |
| A | SEP841 | |
| B | SEP840 | |
| B | SEP841 | |
| Chain | Residue | Details |
| A | TPO844 | |
| B | TPO844 | |
