Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| D | 0008233 | molecular_function | peptidase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| E | 0008233 | molecular_function | peptidase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| F | 0008233 | molecular_function | peptidase activity |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 117 |
| Chain | Residue |
| A | LYS14 |
| A | GLN16 |
| A | ARG77 |
| A | LEU78 |
| A | PRO79 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG C 117 |
| Chain | Residue |
| C | ARG77 |
| C | LEU78 |
| C | PRO79 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PEG E 117 |
| Chain | Residue |
| E | ARG77 |
| E | PRO79 |
| E | GLN16 |
| site_id | AC4 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR CHAIN I OF STATINE-CONTAINING INHIBITOR |
| Chain | Residue |
| A | ARG10 |
| A | LEU30 |
| A | ASP32 |
| A | GLY34 |
| A | ALA35 |
| A | ASP36 |
| A | MET37 |
| A | THR54 |
| A | SER55 |
| A | VAL56 |
| A | LEU57 |
| A | TRP98 |
| B | ARG10 |
| B | ASP32 |
| B | GLY34 |
| B | ALA35 |
| B | ASP36 |
| B | SER55 |
| B | VAL56 |
| B | LEU57 |
| B | GLY58 |
| B | ALA59 |
| B | GLN62 |
| B | TRP98 |
| B | ILE100 |
| I | HOH18 |
| site_id | AC5 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR CHAIN J OF STATINE-CONTAINING INHIBITOR |
| Chain | Residue |
| C | ARG10 |
| C | ASP32 |
| C | GLY34 |
| C | ALA35 |
| C | ASP36 |
| C | MET37 |
| C | SER55 |
| C | VAL56 |
| C | LEU57 |
| C | GLY58 |
| C | ALA59 |
| C | LEU91 |
| C | TRP98 |
| D | ARG10 |
| D | ASP32 |
| D | GLY34 |
| D | ALA35 |
| D | ASP36 |
| D | MET37 |
| D | SER55 |
| D | VAL56 |
| D | LEU57 |
| D | GLY58 |
| D | ALA59 |
| D | GLN62 |
| D | LEU91 |
| D | TRP98 |
| J | HOH105 |
| J | HOH126 |
| J | HOH283 |
| J | HOH284 |
| site_id | AC6 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR CHAIN K OF STATINE-CONTAINING INHIBITOR |
| Chain | Residue |
| E | ARG10 |
| E | LEU30 |
| E | ASP32 |
| E | GLY34 |
| E | ALA35 |
| E | ASP36 |
| E | MET37 |
| E | SER55 |
| E | VAL56 |
| E | LEU57 |
| E | GLY58 |
| E | LEU91 |
| E | TRP98 |
| F | ARG10 |
| F | LEU30 |
| F | ASP32 |
| F | GLY34 |
| F | ALA35 |
| F | ASP36 |
| F | MET37 |
| F | SER55 |
| F | VAL56 |
| F | LEU57 |
| F | GLY58 |
| F | LEU91 |
| F | TRP98 |
| K | HOH100 |
| K | HOH192 |
| K | HOH285 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADMTVI |
| Chain | Residue | Details |
| A | ALA29-ILE40 | |
