3LHD

Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-homocysteine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008033	biological_process	tRNA processing
A	0008168	molecular_function	methyltransferase activity
A	0016740	molecular_function	transferase activity
A	0030488	biological_process	tRNA methylation
A	0031515	cellular_component	tRNA (m1A) methyltransferase complex
A	0032259	biological_process	methylation
A	0043827	molecular_function	tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
A	0160107	molecular_function	tRNA (adenine(58)-N1)-methyltransferase activity
B	0008033	biological_process	tRNA processing
B	0008168	molecular_function	methyltransferase activity
B	0016740	molecular_function	transferase activity
B	0030488	biological_process	tRNA methylation
B	0031515	cellular_component	tRNA (m1A) methyltransferase complex
B	0032259	biological_process	methylation
B	0043827	molecular_function	tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
B	0160107	molecular_function	tRNA (adenine(58)-N1)-methyltransferase activity
C	0008033	biological_process	tRNA processing
C	0008168	molecular_function	methyltransferase activity
C	0016740	molecular_function	transferase activity
C	0030488	biological_process	tRNA methylation
C	0031515	cellular_component	tRNA (m1A) methyltransferase complex
C	0032259	biological_process	methylation
C	0043827	molecular_function	tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
C	0160107	molecular_function	tRNA (adenine(58)-N1)-methyltransferase activity
D	0008033	biological_process	tRNA processing
D	0008168	molecular_function	methyltransferase activity
D	0016740	molecular_function	transferase activity
D	0030488	biological_process	tRNA methylation
D	0031515	cellular_component	tRNA (m1A) methyltransferase complex
D	0032259	biological_process	methylation
D	0043827	molecular_function	tRNA (adenine(57)-N1)/(adenine(58)-N1)-methyltransferase activity
D	0160107	molecular_function	tRNA (adenine(58)-N1)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE SAH C 301

Chain	Residue
C	GLY101
C	PRO195
C	HOH276
C	GLY103
C	GLU125
C	ILE126
C	PHE130
C	LYS152
C	ASP153
C	ILE154
C	TYR155

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SAH A 301

Chain	Residue
A	GLY101
A	GLY103
A	GLU125
A	ILE126
A	PHE130
A	ASP153
A	ILE154
A	TYR155
A	ASP169
A	PRO171

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site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SAH B 301

Chain	Residue
B	GLY101
B	GLY103
B	GLU125
B	ILE126
B	PHE130
B	LYS152
B	ASP153
B	ILE154
B	TYR155
B	ASP169
B	LEU170
B	HOH271
B	HOH277

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site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE SAH D 301

Chain	Residue
D	GLY101
D	GLY103
D	GLU125
D	ILE126
D	ARG127
D	PHE130
D	ASP153
D	ILE154
D	TYR155
D	ASP169
D	LEU170
D	PRO171
D	PRO195
D	GLN199

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING:

Chain	Residue	Details
C	SER104
A	SER104
B	SER104
D	SER104

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00952, ECO:0000269|PubMed:20483913

Chain	Residue	Details
C	GLU125
D	GLU125
D	ASP153
D	ASP169
C	ASP153
C	ASP169
A	GLU125
A	ASP153
A	ASP169
B	GLU125
B	ASP153
B	ASP169

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