3LG2

A Ykr043C/ fructose-1,6-bisphosphate product complex following ligand soaking

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0016491	molecular_function	oxidoreductase activity
A	0016787	molecular_function	hydrolase activity
A	0046390	biological_process	ribose phosphate biosynthetic process
A	0050278	molecular_function	sedoheptulose-bisphosphatase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0016491	molecular_function	oxidoreductase activity
B	0016787	molecular_function	hydrolase activity
B	0046390	biological_process	ribose phosphate biosynthetic process
B	0050278	molecular_function	sedoheptulose-bisphosphatase activity
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0016491	molecular_function	oxidoreductase activity
C	0016787	molecular_function	hydrolase activity
C	0046390	biological_process	ribose phosphate biosynthetic process
C	0050278	molecular_function	sedoheptulose-bisphosphatase activity
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0016491	molecular_function	oxidoreductase activity
D	0016787	molecular_function	hydrolase activity
D	0046390	biological_process	ribose phosphate biosynthetic process
D	0050278	molecular_function	sedoheptulose-bisphosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 A 302

Chain	Residue
A	ARG12
A	HIS13
A	THR25
A	ARG69
A	GLU99
A	HIS176
A	GLY177
A	HOH272

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 B 300

Chain	Residue
A	HIS268
B	HIS178
B	ARG181
A	HIS244

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 B 272

Chain	Residue
A	HIS178
A	ARG181
B	HIS244
B	HIS268

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 B 302

Chain	Residue
B	ARG12
B	HIS13
B	THR25
B	ARG69
B	GLU99
B	HIS176
B	GLY177

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 C 300

Chain	Residue
C	HIS178
C	ARG181
D	HIS244
D	HIS268

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 C 302

Chain	Residue
C	ARG12
C	HIS13
C	THR25
C	ARG69
C	GLU99
C	TYR102
C	HIS176
C	GLY177
C	HOH273

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 C 272

Chain	Residue
C	HIS244
C	GLN267
C	HIS268
D	HIS178
D	ARG181

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 D 302

Chain	Residue
D	ARG12
D	HIS13
D	THR25
D	ARG69
D	GLU99
D	HIS176
D	GLY177

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000269|PubMed:20427268

Chain	Residue	Details
A	HIS13
B	HIS13
C	HIS13
D	HIS13

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:20427268

Chain	Residue	Details
A	GLU99
B	GLU99
C	GLU99
D	GLU99

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:20427268

Chain	Residue	Details
A	ARG12
B	GLU99
B	ARG181
B	HIS244
C	ARG12
C	TYR24
C	ARG69
C	GLU99
C	ARG181
C	HIS244
D	ARG12
A	TYR24
D	TYR24
D	ARG69
D	GLU99
D	ARG181
D	HIS244
A	ARG69
A	GLU99
A	ARG181
A	HIS244
B	ARG12
B	TYR24
B	ARG69

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000305|PubMed:20427268

Chain	Residue	Details
A	HIS176
B	HIS176
C	HIS176
D	HIS176

---