3LF2
NADPH Bound Structure of the Short Chain Oxidoreductase Q9HYA2 from Pseudomonas aeruginosa PAO1 Containing an Atypical Catalytic Center
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| A | 0017000 | biological_process | antibiotic biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| B | 0017000 | biological_process | antibiotic biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| C | 0017000 | biological_process | antibiotic biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050661 | molecular_function | NADP binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
| D | 0017000 | biological_process | antibiotic biosynthetic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE NDP A 301 |
| Chain | Residue |
| A | GLY15 |
| A | VAL68 |
| A | ALA95 |
| A | GLY96 |
| A | SER17 |
| A | SER18 |
| A | ALA39 |
| A | ARG40 |
| A | ASP41 |
| A | ARG44 |
| A | CYS66 |
| A | ASP67 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | LEU148 |
| A | MET156 |
| A | ARG163 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 301 |
| Chain | Residue |
| B | GLY15 |
| B | ALA39 |
| B | ARG40 |
| B | ARG44 |
| B | HOH443 |
| B | HOH454 |
| B | HOH475 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | SER18 |
| B | GLY19 |
| B | SER194 |
| B | GLY195 |
| B | HOH496 |
| B | HOH523 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NDP C 301 |
| Chain | Residue |
| C | GLY15 |
| C | SER17 |
| C | SER18 |
| C | ALA39 |
| C | ARG40 |
| C | ASP41 |
| C | CYS66 |
| C | ASP67 |
| C | VAL68 |
| C | ALA95 |
| C | GLY96 |
| C | GLN97 |
| C | HOH448 |
| C | HOH466 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 302 |
| Chain | Residue |
| C | LEU148 |
| C | THR159 |
| C | ARG163 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 301 |
| Chain | Residue |
| D | GLY15 |
| D | ALA39 |
| D | ARG40 |
| D | HOH440 |
| D | HOH459 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 302 |
| Chain | Residue |
| D | SER18 |
| D | GLY19 |
| D | ARG44 |
| D | GLY195 |
| D | ARG198 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 303 |
| Chain | Residue |
| D | SER146 |
| D | LEU148 |
| D | ARG163 |
