3LDV

1.77 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004590	molecular_function	orotidine-5'-phosphate decarboxylase activity
A	0005829	cellular_component	cytosol
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0044205	biological_process	'de novo' UMP biosynthetic process
B	0004590	molecular_function	orotidine-5'-phosphate decarboxylase activity
B	0005829	cellular_component	cytosol
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0044205	biological_process	'de novo' UMP biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 232

Chain	Residue
A	ASP26
A	HOH330
A	HOH487
A	HOH516

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 233

Chain	Residue
A	PRO67
A	ASN68

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 234

Chain	Residue
A	GLU220
A	ILE25
A	ASP26
A	THR29

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 232

Chain	Residue
B	PRO67
B	ASN68

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 233

Chain	Residue
B	GLY107
B	LYS108
B	GLN128
B	HOH328

---

Functional Information from PROSITE/UniProt

site_id	PS00156
Number of Residues	14
Details	OMPDECASE Orotidine 5'-phosphate decarboxylase active site. VFlDlKfhDIPnTC

Chain	Residue	Details
A	VAL57-CYS70

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01200","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01200","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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