3LD9
Crystal structure of thymidylate kinase from Ehrlichia chaffeensis at 2.15A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004798 | molecular_function | dTMP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| B | 0004798 | molecular_function | dTMP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006227 | biological_process | dUDP biosynthetic process |
| B | 0006233 | biological_process | dTDP biosynthetic process |
| B | 0006235 | biological_process | dTTP biosynthetic process |
| C | 0004798 | molecular_function | dTMP kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006227 | biological_process | dUDP biosynthetic process |
| C | 0006233 | biological_process | dTDP biosynthetic process |
| C | 0006235 | biological_process | dTTP biosynthetic process |
| D | 0004798 | molecular_function | dTMP kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0006227 | biological_process | dUDP biosynthetic process |
| D | 0006233 | biological_process | dTDP biosynthetic process |
| D | 0006235 | biological_process | dTTP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 300 |
| Chain | Residue |
| A | ILE8 |
| A | ASP9 |
| A | GLY10 |
| A | SER11 |
| A | GLY12 |
| A | LYS13 |
| A | THR14 |
| A | HOH256 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 300 |
| Chain | Residue |
| B | ASP9 |
| B | GLY10 |
| B | SER11 |
| B | GLY12 |
| B | LYS13 |
| B | THR14 |
| B | HOH260 |
| B | HOH275 |
| B | ILE8 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 301 |
| Chain | Residue |
| B | GLU38 |
| B | ARG71 |
| B | ARG93 |
| B | PHE94 |
| B | THR98 |
| B | HOH204 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 300 |
| Chain | Residue |
| C | ILE8 |
| C | GLY10 |
| C | SER11 |
| C | GLY12 |
| C | LYS13 |
| C | THR14 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 300 |
| Chain | Residue |
| D | ASP9 |
| D | GLY10 |
| D | SER11 |
| D | GLY12 |
| D | LYS13 |
| D | THR14 |
| D | HOH210 |
| D | HOH237 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 301 |
| Chain | Residue |
| D | GLU38 |
| D | PHE67 |
| D | ARG71 |
| D | PHE94 |
| D | THR98 |
| D | HOH282 |
Functional Information from PROSITE/UniProt
| site_id | PS01331 |
| Number of Residues | 13 |
| Details | THYMIDYLATE_KINASE Thymidylate kinase signature. ICDRFidSTiAYQ |
| Chain | Residue | Details |
| A | ILE90-GLN102 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00165","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
