3LBW

High resolution crystal structure of transmembrane domain of M2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015078	molecular_function	proton transmembrane transporter activity
A	0033644	cellular_component	host cell membrane
A	0055036	cellular_component	virion membrane
A	1902600	biological_process	proton transmembrane transport
B	0015078	molecular_function	proton transmembrane transporter activity
B	0033644	cellular_component	host cell membrane
B	0055036	cellular_component	virion membrane
B	1902600	biological_process	proton transmembrane transport
C	0015078	molecular_function	proton transmembrane transporter activity
C	0033644	cellular_component	host cell membrane
C	0055036	cellular_component	virion membrane
C	1902600	biological_process	proton transmembrane transport
D	0015078	molecular_function	proton transmembrane transporter activity
D	0033644	cellular_component	host cell membrane
D	0055036	cellular_component	virion membrane
D	1902600	biological_process	proton transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069

Chain	Residue	Details
A	HIS37
B	HIS37
C	HIS37
D	HIS37

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069

Chain	Residue	Details
A	TRP41
B	TRP41
C	TRP41
D	TRP41

---