Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
| B | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
| B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KBT A 561 |
| Chain | Residue |
| A | LEU100 |
| A | LEU234 |
| A | HIS235 |
| A | PRO236 |
| A | TYR318 |
| A | HOH586 |
| A | LYS101 |
| A | LYS103 |
| A | TYR181 |
| A | TYR188 |
| A | VAL189 |
| A | GLY190 |
| A | PHE227 |
| A | TRP229 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 562 |
| Chain | Residue |
| A | ARG211 |
| A | GLY436 |
| A | ALA437 |
| A | GLU438 |
| A | ASN460 |
| A | ARG461 |
| B | ALA288 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 563 |
| Chain | Residue |
| A | GLY436 |
| A | ARG461 |
| A | HOH568 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 564 |
| Chain | Residue |
| A | ARG211 |
| A | ASN460 |
| B | THR286 |
| B | ALA288 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 565 |
| Chain | Residue |
| A | SER515 |
| A | GLU516 |
| A | LEU517 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 561 |
| Chain | Residue |
| A | LYS11 |
| B | PRO55 |
| B | TYR56 |
| B | LYS126 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 562 |
| Chain | Residue |
| B | LEU234 |
| B | HIS235 |
| B | TRP239 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP110 | |
| A | ASP185 | |
| A | ASP186 | |
| B | ASP110 | |
| B | ASP185 | |
| B | ASP186 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP443 | |
| A | ASP498 | |
| B | ASP443 | |
| B | ASP498 | |
| Chain | Residue | Details |
| A | GLU478 | |
| A | ASP549 | |
| B | GLU478 | |
| B | ASP549 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | SITE: Essential for RT p66/p51 heterodimerization => ECO:0000250 |
| Chain | Residue | Details |
| A | TRP401 | |
| A | TRP414 | |
| B | TRP401 | |
| B | TRP414 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease; partial => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE440 | |
| B | PHE440 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU560 | |
| B | LEU560 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | |
| Details | M-CSA 175 |
| site_id | MCSA2 |
| Number of Residues | |
| Details | M-CSA 175 |
