3LA6
Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| B | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| C | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| D | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| E | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| F | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| G | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| H | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| I | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| J | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| K | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| L | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| M | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| N | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| O | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
| P | 0045226 | biological_process | extracellular polysaccharide biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP A 1000 |
| Chain | Residue |
| A | PRO471 |
| A | GLY539 |
| A | MET540 |
| A | THR541 |
| A | PHE542 |
| A | TYR569 |
| A | ASN696 |
| A | SER697 |
| A | CA1001 |
| A | SER473 |
| A | GLN476 |
| A | LYS477 |
| A | ASP480 |
| A | LYS492 |
| A | GLN493 |
| A | SER537 |
| A | ILE538 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 1001 |
| Chain | Residue |
| A | THR541 |
| A | ASP564 |
| A | ADP1000 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP B 1000 |
| Chain | Residue |
| B | PRO471 |
| B | LEU472 |
| B | SER473 |
| B | GLN476 |
| B | ASP480 |
| B | GLN493 |
| B | SER537 |
| B | ILE538 |
| B | GLY539 |
| B | MET540 |
| B | THR541 |
| B | PHE542 |
| B | TYR569 |
| B | ASN696 |
| B | SER697 |
| B | CA1001 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 1001 |
| Chain | Residue |
| B | THR541 |
| B | ASP564 |
| B | ADP1000 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP C 1000 |
| Chain | Residue |
| C | PRO471 |
| C | LEU472 |
| C | SER473 |
| C | GLN476 |
| C | ASP480 |
| C | LYS492 |
| C | GLN493 |
| C | SER537 |
| C | ILE538 |
| C | GLY539 |
| C | MET540 |
| C | THR541 |
| C | PHE542 |
| C | TYR569 |
| C | ASN696 |
| C | SER697 |
| C | CA1001 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA C 1001 |
| Chain | Residue |
| C | THR541 |
| C | ADP1000 |
| site_id | AC7 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP D 1000 |
| Chain | Residue |
| D | PRO471 |
| D | LEU472 |
| D | SER473 |
| D | GLN476 |
| D | ASP480 |
| D | LYS492 |
| D | GLN493 |
| D | SER537 |
| D | ILE538 |
| D | GLY539 |
| D | MET540 |
| D | THR541 |
| D | PHE542 |
| D | TYR569 |
| D | ASN696 |
| D | SER697 |
| D | CA1001 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA D 1001 |
| Chain | Residue |
| D | THR541 |
| D | ASP564 |
| D | ADP1000 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP E 1000 |
| Chain | Residue |
| E | PRO471 |
| E | LEU472 |
| E | SER473 |
| E | GLN476 |
| E | ASP480 |
| E | LYS492 |
| E | GLN493 |
| E | SER537 |
| E | ILE538 |
| E | GLY539 |
| E | MET540 |
| E | THR541 |
| E | PHE542 |
| E | TYR569 |
| E | ASN696 |
| E | SER697 |
| E | CA1001 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA E 1001 |
| Chain | Residue |
| E | THR541 |
| E | ASP642 |
| E | ADP1000 |
| site_id | BC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP F 1000 |
| Chain | Residue |
| F | LEU472 |
| F | SER473 |
| F | GLN476 |
| F | ASP480 |
| F | SER537 |
| F | ILE538 |
| F | GLY539 |
| F | MET540 |
| F | THR541 |
| F | PHE542 |
| F | TYR569 |
| F | ASN696 |
| F | SER697 |
| F | CA1001 |
| F | PRO471 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA F 1001 |
| Chain | Residue |
| F | THR541 |
| F | ADP1000 |
| site_id | BC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ADP G 1000 |
| Chain | Residue |
| G | ILE470 |
| G | PRO471 |
| G | LEU472 |
| G | SER473 |
| G | GLN476 |
| G | LYS477 |
| G | ASP480 |
| G | GLN493 |
| G | SER537 |
| G | ILE538 |
| G | GLY539 |
| G | MET540 |
| G | THR541 |
| G | PHE542 |
| G | TYR569 |
| G | ASN696 |
| G | SER697 |
| G | CA1001 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA G 1001 |
| Chain | Residue |
| G | THR541 |
| G | ASP564 |
| G | ADP1000 |
| site_id | BC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP H 1000 |
| Chain | Residue |
| H | PRO471 |
| H | LEU472 |
| H | SER473 |
| H | GLN476 |
| H | ASP480 |
| H | GLN493 |
| H | SER537 |
| H | ILE538 |
| H | GLY539 |
| H | MET540 |
| H | THR541 |
| H | PHE542 |
| H | TYR569 |
| H | ASN696 |
| H | SER697 |
| H | CA1001 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA H 1001 |
| Chain | Residue |
| H | THR541 |
| H | ASP564 |
| H | ADP1000 |
| site_id | BC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP I 1000 |
| Chain | Residue |
| I | PRO471 |
| I | LEU472 |
| I | SER473 |
| I | GLN476 |
| I | ASP480 |
| I | LYS492 |
| I | GLN493 |
| I | SER537 |
| I | ILE538 |
| I | GLY539 |
| I | MET540 |
| I | THR541 |
| I | PHE542 |
| I | TYR569 |
| I | ASN696 |
| I | SER697 |
| I | CA1001 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA I 1001 |
| Chain | Residue |
| I | THR541 |
| I | ASP564 |
| I | ADP1000 |
| J | TYR715 |
| site_id | CC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP J 1000 |
| Chain | Residue |
| J | PRO471 |
| J | LEU472 |
| J | SER473 |
| J | GLN476 |
| J | ASP480 |
| J | LYS492 |
| J | GLN493 |
| J | SER537 |
| J | ILE538 |
| J | GLY539 |
| J | MET540 |
| J | THR541 |
| J | PHE542 |
| J | TYR569 |
| J | ASN696 |
| J | SER697 |
| J | CA1001 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA J 1001 |
| Chain | Residue |
| J | THR541 |
| J | ADP1000 |
| site_id | CC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP K 1000 |
| Chain | Residue |
| K | PRO471 |
| K | LEU472 |
| K | SER473 |
| K | GLN476 |
| K | ASP480 |
| K | LYS492 |
| K | GLN493 |
| K | SER537 |
| K | ILE538 |
| K | GLY539 |
| K | MET540 |
| K | THR541 |
| K | PHE542 |
| K | TYR569 |
| K | ASN696 |
| K | CA1001 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA K 1001 |
| Chain | Residue |
| K | THR541 |
| K | ASP564 |
| K | ADP1000 |
| L | TYR715 |
| site_id | CC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP L 1000 |
| Chain | Residue |
| L | PRO471 |
| L | LEU472 |
| L | SER473 |
| L | GLN476 |
| L | ASP480 |
| L | SER537 |
| L | ILE538 |
| L | GLY539 |
| L | MET540 |
| L | THR541 |
| L | PHE542 |
| L | TYR569 |
| L | ASN696 |
| L | SER697 |
| L | CA1001 |
| site_id | CC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA L 1001 |
| Chain | Residue |
| L | THR541 |
| L | ADP1000 |
| site_id | CC7 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP M 1000 |
| Chain | Residue |
| M | PRO471 |
| M | LEU472 |
| M | SER473 |
| M | GLN476 |
| M | ASP480 |
| M | SER537 |
| M | ILE538 |
| M | GLY539 |
| M | MET540 |
| M | THR541 |
| M | PHE542 |
| M | TYR569 |
| M | ASN696 |
| M | SER697 |
| M | CA1001 |
| site_id | CC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA M 1001 |
| Chain | Residue |
| M | THR541 |
| M | ADP1000 |
| site_id | CC9 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ADP N 1000 |
| Chain | Residue |
| N | PRO471 |
| N | LEU472 |
| N | SER473 |
| N | GLN476 |
| N | ASP480 |
| N | LYS492 |
| N | GLN493 |
| N | SER537 |
| N | ILE538 |
| N | GLY539 |
| N | MET540 |
| N | THR541 |
| N | PHE542 |
| N | TYR569 |
| N | ASN696 |
| N | SER697 |
| N | CA1001 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA N 1001 |
| Chain | Residue |
| N | THR541 |
| N | ADP1000 |
| site_id | DC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP O 1000 |
| Chain | Residue |
| O | PRO471 |
| O | LEU472 |
| O | SER473 |
| O | GLN476 |
| O | ASP480 |
| O | GLN493 |
| O | SER537 |
| O | ILE538 |
| O | GLY539 |
| O | MET540 |
| O | THR541 |
| O | PHE542 |
| O | TYR569 |
| O | ASN696 |
| O | CA1001 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA O 1001 |
| Chain | Residue |
| O | THR541 |
| O | ASP564 |
| O | ADP1000 |
| site_id | DC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP P 1000 |
| Chain | Residue |
| P | PRO471 |
| P | LEU472 |
| P | SER473 |
| P | GLN476 |
| P | ASP480 |
| P | SER537 |
| P | ILE538 |
| P | GLY539 |
| P | MET540 |
| P | THR541 |
| P | PHE542 |
| P | TYR569 |
| P | ASN696 |
| P | SER697 |
| P | CA1001 |
| site_id | DC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA P 1001 |
| Chain | Residue |
| P | THR541 |
| P | ADP1000 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | MOD_RES: Phosphotyrosine; by autocatalysis => ECO:0000305|PubMed:12851388 |
| Chain | Residue | Details |
| A | TYR569 | |
| J | TYR569 | |
| K | TYR569 | |
| L | TYR569 | |
| M | TYR569 | |
| N | TYR569 | |
| O | TYR569 | |
| P | TYR569 | |
| B | TYR569 | |
| C | TYR569 | |
| D | TYR569 | |
| E | TYR569 | |
| F | TYR569 | |
| G | TYR569 | |
| H | TYR569 | |
| I | TYR569 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 80 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000305|PubMed:12851388 |
| Chain | Residue | Details |
| A | TYR708 | |
| B | TYR715 | |
| C | TYR708 | |
| C | TYR710 | |
| C | TYR711 | |
| C | TYR713 | |
| C | TYR715 | |
| D | TYR708 | |
| D | TYR710 | |
| D | TYR711 | |
| D | TYR713 | |
| A | TYR710 | |
| D | TYR715 | |
| E | TYR708 | |
| E | TYR710 | |
| E | TYR711 | |
| E | TYR713 | |
| E | TYR715 | |
| F | TYR708 | |
| F | TYR710 | |
| F | TYR711 | |
| F | TYR713 | |
| A | TYR711 | |
| F | TYR715 | |
| G | TYR708 | |
| G | TYR710 | |
| G | TYR711 | |
| G | TYR713 | |
| G | TYR715 | |
| H | TYR708 | |
| H | TYR710 | |
| H | TYR711 | |
| H | TYR713 | |
| A | TYR713 | |
| H | TYR715 | |
| I | TYR708 | |
| I | TYR710 | |
| I | TYR711 | |
| I | TYR713 | |
| I | TYR715 | |
| J | TYR708 | |
| J | TYR710 | |
| J | TYR711 | |
| J | TYR713 | |
| A | TYR715 | |
| J | TYR715 | |
| K | TYR708 | |
| K | TYR710 | |
| K | TYR711 | |
| K | TYR713 | |
| K | TYR715 | |
| L | TYR708 | |
| L | TYR710 | |
| L | TYR711 | |
| L | TYR713 | |
| B | TYR708 | |
| L | TYR715 | |
| M | TYR708 | |
| M | TYR710 | |
| M | TYR711 | |
| M | TYR713 | |
| M | TYR715 | |
| N | TYR708 | |
| N | TYR710 | |
| N | TYR711 | |
| N | TYR713 | |
| B | TYR710 | |
| N | TYR715 | |
| O | TYR708 | |
| O | TYR710 | |
| O | TYR711 | |
| O | TYR713 | |
| O | TYR715 | |
| P | TYR708 | |
| P | TYR710 | |
| P | TYR711 | |
| P | TYR713 | |
| B | TYR711 | |
| P | TYR715 | |
| B | TYR713 |
