3L8H

Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from B. bronchiseptica complexed with magnesium and phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005975	biological_process	carbohydrate metabolic process
A	0008270	molecular_function	zinc ion binding
A	0009244	biological_process	lipopolysaccharide core region biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0034200	molecular_function	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
A	0046872	molecular_function	metal ion binding
A	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B	0000287	molecular_function	magnesium ion binding
B	0005737	cellular_component	cytoplasm
B	0005975	biological_process	carbohydrate metabolic process
B	0008270	molecular_function	zinc ion binding
B	0009244	biological_process	lipopolysaccharide core region biosynthetic process
B	0016787	molecular_function	hydrolase activity
B	0016791	molecular_function	phosphatase activity
B	0034200	molecular_function	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
B	0046872	molecular_function	metal ion binding
B	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C	0000287	molecular_function	magnesium ion binding
C	0005737	cellular_component	cytoplasm
C	0005975	biological_process	carbohydrate metabolic process
C	0008270	molecular_function	zinc ion binding
C	0009244	biological_process	lipopolysaccharide core region biosynthetic process
C	0016787	molecular_function	hydrolase activity
C	0016791	molecular_function	phosphatase activity
C	0034200	molecular_function	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
C	0046872	molecular_function	metal ion binding
C	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D	0000287	molecular_function	magnesium ion binding
D	0005737	cellular_component	cytoplasm
D	0005975	biological_process	carbohydrate metabolic process
D	0008270	molecular_function	zinc ion binding
D	0009244	biological_process	lipopolysaccharide core region biosynthetic process
D	0016787	molecular_function	hydrolase activity
D	0016791	molecular_function	phosphatase activity
D	0034200	molecular_function	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase activity
D	0046872	molecular_function	metal ion binding
D	0097171	biological_process	ADP-L-glycero-beta-D-manno-heptose biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Nucleophile

Chain	Residue	Details
A	ASP7
B	ASP7
C	ASP7
D	ASP7

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	ASP9
B	ASP9
C	ASP9
D	ASP9

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:20050614

Chain	Residue	Details
A	ASP7
C	ARG57
C	ARG100
C	ARG129
D	ASP7
D	ARG57
D	ARG100
D	ARG129
A	ARG57
A	ARG100
A	ARG129
B	ASP7
B	ARG57
B	ARG100
B	ARG129
C	ASP7

---

site_id	SWS_FT_FI4
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:20050614, ECO:0007744|PDB:3L8H

Chain	Residue	Details
A	ASP9
B	CYS99
C	ASP9
C	CYS89
C	HIS91
C	CYS97
C	CYS99
D	ASP9
D	CYS89
D	HIS91
D	CYS97
A	CYS89
D	CYS99
A	HIS91
A	CYS97
A	CYS99
B	ASP9
B	CYS89
B	HIS91
B	CYS97

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	BINDING:

Chain	Residue	Details
A	ASP15
A	THR50
B	ASP15
B	THR50
C	ASP15
C	THR50
D	ASP15
D	THR50

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	BINDING: BINDING => ECO:0007744|PDB:3L8H

Chain	Residue	Details
A	ASP126
B	ASP126
C	ASP126
D	ASP126

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	SITE: Stabilizes the phosphoryl group => ECO:0000250

Chain	Residue	Details
A	THR50
A	LYS101
B	THR50
B	LYS101
C	THR50
C	LYS101
D	THR50
D	LYS101

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	SITE: Contributes to substrate recognition => ECO:0000250

Chain	Residue	Details
A	ARG100
B	ARG100
C	ARG100
D	ARG100

---